ZFIN ID: ZDB-FIG-110317-22
Cdkn1b is expressed in the developing lateral somite.
In situ hybridization of 15 ss embryos for cdkn1a, cdkn1b and cdkn1b-like, also showing cdkn1c for comparison. Dorsal view flatmounts, anterior to top. Boxed areas are magnified at right. Cdkn1a mRNA is not detected above background. Cdkn1b mRNA appears in the lateral region of each somite shortly after its formation. Cdkn1bl mRNA is barely detectable above background in somites. In contrast, cdkn1c mRNA is readily detected in notochord, muscle and CNS. Bars: 50 μm.
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Reprinted from Developmental Biology, 350(2), Osborn, D.P., Li, K., Hinits, Y., and Hughes, S.M., Cdkn1c drives muscle differentiation through a positive feedback loop with Myod, 464-475, Copyright
(2011) with permission from Elsevier.
Full text @ Dev. Biol.