ZFIN ID: ZDB-FIG-110317-22
Osborn et al., 2011 - Cdkn1c drives muscle differentiation through a positive feedback loop with Myod. Developmental Biology   350(2):464-475 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage: 14-19 somites

Fig. S4 Cdkn1b is expressed in the developing lateral somite.

In situ hybridization of 15 ss embryos for cdkn1a, cdkn1b and cdkn1b-like, also showing cdkn1c for comparison. Dorsal view flatmounts, anterior to top. Boxed areas are magnified at right. Cdkn1a mRNA is not detected above background. Cdkn1b mRNA appears in the lateral region of each somite shortly after its formation. Cdkn1bl mRNA is barely detectable above background in somites. In contrast, cdkn1c mRNA is readily detected in notochord, muscle and CNS. Bars: 50 μm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
cdkn1a WT standard conditions 14-19 somites Not Detected adaxial cell ISH
cdkn1ba WT standard conditions 14-19 somites Not Detected adaxial cell ISH
cdkn1bb WT standard conditions 14-19 somites Not Detected adaxial cell ISH
14-19 somites somite lateral region ISH
cdkn1ca WT standard conditions 14-19 somites adaxial cell ISH
14-19 somites fast muscle myoblast ISH
14-19 somites notochord ISH
14-19 somites slow muscle cell ISH
14-19 somites spinal cord neural tube ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
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Reprinted from Developmental Biology, 350(2), Osborn, D.P., Li, K., Hinits, Y., and Hughes, S.M., Cdkn1c drives muscle differentiation through a positive feedback loop with Myod, 464-475, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.