ZFIN ID: ZDB-FIG-101029-6
Verbruggen et al., 2010 - The Pax6b homeodomain is dispensable for pancreatic endocrine cell differentiation in zebrafish. The Journal of biological chemistry   285(18):13863-13873 Full text @ J. Biol. Chem.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage: Protruding-mouth
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Protruding-mouth

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
gcga AB control Protruding-mouth pancreatic A cell ISH
AB + MO4-pax6b standard conditions Protruding-mouth pancreatic A cell ISH
AB + MO5-pax6b standard conditions Protruding-mouth pancreatic A cell ISH
AB + MO5-pax6b + MO8-pax6b standard conditions Protruding-mouth pancreatic A cell ISH
AB + MO6-pax6b standard conditions Protruding-mouth pancreatic A cell ISH
AB + MO6-pax6b + MO7-pax6b standard conditions Protruding-mouth pancreatic A cell ISH
ghrl AB control Protruding-mouth Not Detected endocrine pancreas peptide hormone secreting cell ISH
AB + MO4-pax6b standard conditions Protruding-mouth endocrine pancreas peptide hormone secreting cell ISH
AB + MO5-pax6b standard conditions Protruding-mouth endocrine pancreas peptide hormone secreting cell ISH
AB + MO5-pax6b + MO8-pax6b standard conditions Protruding-mouth endocrine pancreas peptide hormone secreting cell ISH
AB + MO6-pax6b standard conditions Protruding-mouth endocrine pancreas peptide hormone secreting cell ISH
AB + MO6-pax6b + MO7-pax6b standard conditions Protruding-mouth Not Detected endocrine pancreas peptide hormone secreting cell ISH
ins AB control Protruding-mouth pancreatic B cell ISH
AB + MO4-pax6b standard conditions Protruding-mouth pancreatic B cell ISH
AB + MO5-pax6b standard conditions Protruding-mouth pancreatic B cell ISH
AB + MO5-pax6b + MO8-pax6b standard conditions Protruding-mouth Not Detected pancreatic B cell ISH
AB + MO6-pax6b standard conditions Protruding-mouth pancreatic B cell ISH
AB + MO6-pax6b + MO7-pax6b standard conditions Protruding-mouth pancreatic B cell ISH
sst2 AB control Protruding-mouth D cell ISH
AB + MO4-pax6b standard conditions Protruding-mouth D cell ISH
AB + MO5-pax6b standard conditions Protruding-mouth D cell ISH
AB + MO5-pax6b + MO8-pax6b standard conditions Protruding-mouth D cell ISH
AB + MO6-pax6b standard conditions Protruding-mouth D cell ISH
AB + MO6-pax6b + MO7-pax6b standard conditions Protruding-mouth D cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO4-pax6b standard conditions Protruding-mouth D cell decreased amount, abnormal
Protruding-mouth endocrine pancreas peptide hormone secreting cell increased amount, abnormal
Protruding-mouth pancreatic B cell decreased amount, abnormal
AB + MO5-pax6b standard conditions Protruding-mouth D cell decreased amount, abnormal
Protruding-mouth endocrine pancreas peptide hormone secreting cell increased amount, abnormal
Protruding-mouth pancreatic B cell decreased amount, abnormal
AB + MO5-pax6b + MO8-pax6b standard conditions Protruding-mouth D cell decreased amount, abnormal
Protruding-mouth endocrine pancreas peptide hormone secreting cell increased amount, abnormal
Protruding-mouth pancreatic B cell absent, abnormal
AB + MO6-pax6b standard conditions Protruding-mouth D cell decreased amount, abnormal
Protruding-mouth endocrine pancreas peptide hormone secreting cell increased amount, abnormal
Protruding-mouth pancreatic B cell decreased amount, abnormal
AB + MO6-pax6b + MO7-pax6b standard conditions Protruding-mouth D cell normal amount, normal
Protruding-mouth endocrine pancreas peptide hormone secreting cell normal amount, normal
Protruding-mouth pancreatic A cell normal amount, normal
Protruding-mouth pancreatic B cell normal amount, normal
Full text @ J. Biol. Chem.
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