FIGURE

Fig. 6

ID

ZDB-FIG-101025-20

Publication

Wong et al., 2010 - Duplicate dmbx1 genes regulate progenitor cell cycle and differentiation during zebrafish midbrain and retinal development

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Fig. 6

Altered retinal gene expression in morphant embryos. Coronal plastic sections (~ 1 μm) of retina at 72 hpf after whole mount in situ hybridization labeling for progenitor markers from control mMO1a + mMO1b injected (A, C, E), or MO1a + MO1b injected (B, D, F) embryos. Position of the lens (shown in A) is similar for all panels. Arrows in C and D demarcate the ciliary marginal zone (CMZ). Cryosections (~15 μm) of control (G, I, K, M, O, Q) and MO1a + MO1b (H, J, L, N, P, R) embryos immunolabelled with antibodies for indicated differentiation markers (red or green) and counter-stained with DAPI (blue). MO, morpholino.

Expression Data

Genes:	neurod1 otx2b vsx2
Fish:	AB AB + MO1-dmbx1a + MO1-dmbx1b
Knockdown Reagents:	MO1-dmbx1a MO1-dmbx1b
Anatomical Terms:	ciliary marginal zone somatic stem cell eye photoreceptor cell retinal ganglion cell layer retinal inner nuclear layer retinal outer nuclear layer
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	zc7Tg + MO1-dmbx1a + MO1-dmbx1b
Knockdown Reagents:	MO1-dmbx1a MO1-dmbx1b
Observed In:	amacrine cell retina neuronal stem cell retinal bipolar neuron retinal ganglion cell
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.