FIGURE

Fig. 2

ID

ZDB-FIG-100128-2

Publication

Tse et al., 2009 - Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development

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Fig. 2

Comparison of huC expression in morphants of groups II, III and IV zebrafish DUBs at 24 hpf. huC expression at 24 hpf, dorsal view. Decreased huC expression was found in morphants of these 3 groups. Group II has 16 members that showed a typical decreased huC expression (arrows). Group III has 13 members that showed the decreased huC expression with destructive patterning. Lastly, group IV has 4 members that had the most severe decreased and destructive huC expression. All 4 members named otud4, usp5, usp15 and usp25 could not form a normal neuronal pattern in the head region. Arrowheads mark the abnormal patterns in morphants of group III; while arrows indicate the absence of neurons in morphants of group IV.

Expression Data

Gene:	elavl3
Fish:	AB AB + MO1-alg13 AB + MO1-mysm1 AB + MO1-usp1 AB + MO1-usp5 AB + MO1-usp15 AB + MO1-usp19 AB + MO1-usp21 AB + MO1-usp24 AB + MO1-usp25
Knockdown Reagents:	MO1-alg13 MO1-mysm1 MO1-usp1 MO1-usp5 MO1-usp15 MO1-usp19 MO1-usp21 MO1-usp24 MO1-usp25
Anatomical Term:	neuron
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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