ZFIN ID: ZDB-GENE-980526-76
Gene Name: ELAV like neuron-specific RNA binding protein 3
Gene Symbol: elavl3    Nomenclature History

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Previous Names: elavC (1), elrC (1), elrc (1), elav-related C, etID309927.3 (1), huc, HuC, id:ibd1248, wu:fb77b03, zHuC (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have RNA binding activity. Involved in regulation of neurogenesis. Predicted to localize to ribonucleoprotein complex. Is expressed in several structures, including nervous system; neural plate; neural tube; neuronal stem cell; and presumptive structure. Orthologous to human ELAVL3 (ELAV like RNA binding protein 3).
Genome Resources: Alliance (1),  Gene:30732 (1),  Ensembl(GRCz11):ENSDARG00000014420 (2)
GENE EXPRESSION
All Expression Data: 129 figures from 90 publications
Directly Submitted Expression Data: 3 figures (3 images) from Kudoh et al., 2001 [ibd1248]
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-elavl3 N/A 1
DISEASE ASSOCIATED WITH elavl3 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH elavl3 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of neurogenesis (more)
Cellular Component ribonucleoprotein complex (more)
Molecular Function nucleic acid binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA elavl3-201 (1)    Ensembl 1120
elavl3-202 (1)    Ensembl 3227
elavl3-204 (1)    Ensembl 530
ncRNA elavl3-003 (1)    Ensembl 863
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-elavl monoclonal IgG2b Mouse IHC Santa Cruz Biotechnology, Inc.
Life Technologies (Invitrogen)
Abcam plc
MoBiTec Molecular Biotechnology
Molecular Probes, Inc.
377
CONSTRUCTS WITH SEQUENCES FROM elavl3
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(-2.8elavl3:EGFP) elavl3 EGFP Danio rerio 1 4
Tg(elavl3-UBCI:Cerulean) elavl3UBCI Cerulean Danio rerio 1 2
Tg(elavl3:CaMPARI) elavl3 CaMPARI Danio rerio 1 8
Tg(elavl3:CaMPARI2) elavl3 CaMPARI Danio rerio 1 2
Tg(elavl3:Cerulean-Cre) elavl3 CeruleanCre Danio rerio 1 1
tg(elavl3:cochr-egfp) elavl3 CoChREGFP Danio rerio 1 1
Tg(elavl3:Cre) elavl3 Cre Danio rerio 1 1
Tg(elavl3:EGFP) elavl3 EGFP Danio rerio 1 129
tg(elavl3:egfp-aequorin) elavl3 AequorinEGFP Danio rerio 1 2
tg(elavl3:egfp-hsa.dnajc5) elavl3 EGFP Danio rerioHomo sapiens 1 1
tg(elavl3:egfp-map1lc3b) elavl3 EGFPmap1lc3b Danio rerio 1 1
Tg(elavl3:GAL4) elavl3 GAL4 Danio rerio 1 15
Tg(elavl3:GAL4-VP16) elavl3 GAL4VP16 Danio rerio 1 25
Tg(elavl3:GAL4-VP16-mCherry) elavl3 GAL4mCherryVP16 Danio rerio 1 2
Tg(elavl3:GAL80,myl7:EGFP) elavl3myl7 EGFPGAL80 Danio rerio 1 2
Tg(elavl3:GAL80,myl7:TagRFP) elavl3myl7 GAL80TagRFP Danio rerio 1 2
Tg(elavl3:GAL80ts,myl7:TagRFP) elavl3myl7 GAL80tsTagRFP Danio rerio 1 2
Tg(elavl3:GCaMP2) elavl3 GCaMP Danio rerio 1 7
Tg(elavl3:GCaMP3) elavl3 GCaMP Danio rerio 1 7
Tg(elavl3:GCaMP5) elavl3 GCaMP Danio rerio 1 5
Tg(elavl3:GCaMP5G) elavl3 GCaMP Danio rerio 2 58
Tg(elavl3:GCaMP6f) elavl3 GCaMP Danio rerio 1 12
Tg(elavl3:GCaMP6s) elavl3 GCaMP Danio rerio 2 17
tg(elavl3:gfp) elavl3 GFP Danio rerio 1 2
tg(elavl3:grabne1h) elavl3 GRABne Danio rerio 1 1
tg(elavl3:grabne1m) elavl3 GRABne Danio rerio 1 1
tg(elavl3:h2b-gcamp6) elavl3 GCaMP Danio rerio 1 1
Tg(elavl3:H2B-GCaMP6f) elavl3 GCaMP Danio rerio 1 17
tg(elavl3:h2b-gcamp6s) elavl3 GCaMP Danio rerio 1 1
Tg(elavl3:H2B-mKate2) elavl3 mKate2 Danio rerio 1 2
Tg(elavl3:Hsa.H2B-GCaMP6s) elavl3 GCaMP Danio rerioHomo sapiens 1 33
Tg(elavl3:Hsa.HIST2H2BE-RFP) elavl3 RFP Danio rerioHomo sapiens 1 3
Tg(elavl3:IP) elavl3 Danio rerio 1 5
Tg(elavl3:ITETA) elavl3 Danio rerio 6 6
Tg(elavl3:jRCaMP1a) elavl3 RCaMP Danio rerio 1 3
tg(elavl3:jrgeco1b) elavl3 RGECO Danio rerio 1 1
Tg(elavl3:Kaede) elavl3 Kaede Danio rerio 1 49
Tg(elavl3:KALTA4) elavl3 KALTA4 Danio rerio 1 1
Tg(elavl3:LOXP-DsRed-LOXP-EGFP) elavl3 DsRedEGFP Danio rerio 1 2
Tg(elavl3:LY-mCherry) elavl3 LYmCherry Danio rerio 1 2
Tg(elavl3:LY-TagRFP) elavl3 LYTagRFP Danio rerio 1 6
Tg(elavl3:mCherry) elavl3 mCherry Danio rerio 1 7
tg(elavl3:mcherry-hsa.dnajc5) elavl3 mCherry Danio rerioHomo sapiens 1 1
tg(elavl3:mcoln1a) elavl3 mcoln1a Danio rerio 1 1
tg(elavl3:nexs-jrgeco1a) elavl3 NEXSRGECO Danio rerio 1 1
Tg(elavl3:NLS-GCaMP6s) elavl3 GCaMPNLS Danio rerio 1 4
tg(elavl3:nls-mcardinal) elavl3 MCardinalNLS Danio rerio 1 2
Tg(elavl3:ReaChR-TagRFPT) elavl3 ReaChRTagRFPT Danio rerio 1 4
Tg(elavl3:RFP) elavl3 RFP Danio rerio 1 1
tg(elavl3:rscampari-mruby3) elavl3 CaMPARImRuby Danio rerio 1 1
Tg(elavl3:spHGFP) elavl3 spHGFPvamp2 Danio rerio 1 3
tg(elavl3:teta-bmo.ecr-2a-mcherry) elavl3 2AmCherryTETA Bombyx moriDanio rerio 1 1
Tg(elavl3:YC2) elavl3 YC2 Danio rerio 1 17
tg(elavl3:yfp) elavl3 YFP Danio rerio 0 1
Tg1(-2.8elavl3:EGFP) elavl3 EGFP Danio rerio 1 4
Tg1(elavl3:GAL4-VP16) elavl3 GAL4VP16 Danio rerio 1 2
tg1(elavl3:gfp) elavl3 GFP Danio rerio 1 3
tg1(elavl3:yfp) elavl3 YFP Danio rerio 1 2
Tg2(elavl3:Cre) elavl3 Cre Danio rerio 1 1
Tg2(elavl3:EGFP) elavl3 EGFP Danio rerio 1 10
Tg2(elavl3:GAL4) elavl3 GAL4 Danio rerio 1 2
Tg2(elavl3:GAL4-VP16) elavl3 GAL4VP16 Danio rerio 1 17
Tg2(elavl3:GCaMP3) elavl3 GCaMP Danio rerio 1 1
Tg2(elavl3:GCaMP5G) elavl3 GCaMP Danio rerio 2 5
Tg2(elavl3:GCaMP6f) elavl3 GCaMP Danio rerio 1 8
Tg2(elavl3:GCaMP6s) elavl3 GCaMP Danio rerio 1 7
tg2(elavl3:gfp) elavl3 GFP Danio rerio 1 1
Tg3(elavl3:GAL4) elavl3 GAL4 Danio rerio 1 2
Tg3(elavl3:GAL4-VP16) elavl3 GAL4VP16 Danio rerio 2 8
Tg4(elavl3:GAL4) elavl3 GAL4 Danio rerio 1 1
Tg4(elavl3:GAL4-VP16) elavl3 GAL4VP16 Danio rerio 1 1
Tg5(elavl3:GAL4-VP16) elavl3 GAL4VP16 Danio rerio 1 4
Tg6(elavl3:GAL4-VP16) elavl3 GAL4VP16 Danio rerio 1 1
Tg7(elavl3:GAL4-VP16) elavl3 GAL4VP16 Danio rerio 1 3
MARKER RELATIONSHIPS
elavl3 Contained in: [BAC] DKEY-223G14 (1) (order this)
elavl3 Encodes: [EST] fb77b03, ibd1248
[cDNA] MGC:77335 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131449 (1) 1119 nt
Genomic GenBank:CR385086 (1) 193299 nt
Select Tool
Polypeptide UniProtKB:Q6P105 (1) 359 aa
Sequence Information (all 37)
ORTHOLOGY for elavl3 ( Chr: 3 )
CITATIONS (293)