ZFIN ID: ZDB-FIG-071116-17
Blanco et al., 2007 - Snail1a and Snail1b cooperate in the anterior migration of the axial mesendoderm in the zebrafish embryo. Development (Cambridge, England)   134(22):4073-4081 Full text @ Development
Anatomical Terms:
Stage Range: Shield to 90%-epiboly

Fig. 6 The axial mesendoderm is subdivided into different territories with complementary snail1 and E-cadherin (Cdh1) expression. (A-H) Expression of snail1 genes and that of E-cadherin protein. (A,B) At 70% epiboly, snail1a-expressing cells surround the anterior limit of the hgg1- expressing domain and snail1b transcripts are absent from the hgg1-expressing prechordal plate region. (C,D) These expression domains are better observed in sections. (E) The domain of strong snail1a expression surrounding the hgg1-expressing cells is already present at 60% epiboly. (F) Diagram depicting the domains of snail1a, 1b and hgg1 expression in the anterior half of the embryo. (G,H) snail1b and E-cadherin (Cdh1) expression in the posterior half of an embryo at 90% epiboly. Note the complementary domains of snail1b and cadherin expression (compare E with F). (I) Diagram showing the relationship between the expression of snail1 genes and those of hgg1 and ntl. Also note the inverse correlation between snail1 and Cdh1 expression.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
cdh1 WT standard conditions 90%-epiboly axial chorda mesoderm ISH
ctslb WT standard conditions Shield hypoblast ISH
snai1a WT standard conditions Shield margin ISH
Shield yolk syncytial layer ISH
90%-epiboly axial mesoderm ISH
snai1b WT standard conditions Shield hypoblast ISH
Antibody Labeling Details No data available
Phenotype Details No data available
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development