Gene

snai1b

ID
ZDB-GENE-980526-514
Name
snail family zinc finger 1b
Symbol
snai1b Nomenclature History
Previous Names
  • sna2
  • snail-2 (1)
  • snail1b (1)
  • snail2
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including ameboidal-type cell migration; cardiac muscle progenitor cell migration to the midline involved in heart field formation; and posterior lateral line neuromast primordium migration. Predicted to localize to nuclear chromatin. Is expressed in several structures, including ectoderm; heart; mesoderm; neural crest; and trunk. Orthologous to human SNAI1 (snail family transcriptional repressor 1).
Genome Resources
Note
This gene was originally named snail2 (Thisse et al. 1993). In 2004 Manzanares et al. demonstrated that this gene arose from a duplication event in the teleost lineage that resulted in snail1a and snail1b resulting in a gene name change.
Expression
All Expression Data
80 figures from 59 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
13 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With snai1b Human Ortholog
No data available
Associated With snai1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013087 Zinc finger C2H2-type
Homologous_superfamily IPR036236 Zinc finger C2H2 superfamily
Domain Details Per Protein
Protein Length Zinc finger C2H2 superfamily Zinc finger C2H2-type
UniProtKB:Q90414 257
UniProtKB:B3DH44 256
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations