ZFIN ID: ZDB-FIG-070613-41
Chocron et al., 2007 - Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points. Developmental Biology   305(2):577-588 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: 14-19 somites to High-pec
PHENOTYPE:
Fish:
Observed In:
Stage: Prim-5

Fig. S1 Comparable nkx2.5 expression in laf/alk8 siblings (A) and mutant (B) embryos at the 15-somite stage. Heart tube in laf/alk8 siblings jogs to the left (C) while it remains in the middle in mutant embryos (D). Embryos at 28 hpf double stained with vmhc (red color) and amhc (blue color). laf/alk8 sibling (E) and mutant (F) embryos show absence of cardiac looping in the mutant embryo. (A–D) Dorsal views with anterior to the bottom of the panel. (E, F) Ventral views.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
myh6 acvr1ltm110b/+(TU) standard conditions Prim-5 primitive heart tube ISH
acvr1ltm110b/tm110b(TU) standard conditions Prim-5 primitive heart tube ISH
myh7 acvr1ltm110b/+(TU) standard conditions Prim-5 presumptive cardiac ventricle heart tube ISH
acvr1ltm110b/tm110b(TU) standard conditions Prim-5 presumptive cardiac ventricle heart tube ISH
myl7 acvr1ltm110b/+(TU) standard conditions High-pec heart ISH
acvr1ltm110b/tm110b(TU) standard conditions High-pec heart ISH
nkx2.5 acvr1ltm110b/+(TU) standard conditions 14-19 somites lateral plate mesoderm ISH
acvr1ltm110b/tm110b(TU) standard conditions 14-19 somites lateral plate mesoderm ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
acvr1ltm110b/tm110b(TU) standard conditions Prim-5 atrial cardiac muscle cell differentiation process quality, normal
Prim-5 ventricular cardiac muscle cell differentiation process quality, normal
Acknowledgments:
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Reprinted from Developmental Biology, 305(2), Chocron, S., Verhoeven, M.C., Rentzsch, F., Hammerschmidt, M., and Bakkers, J., Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points, 577-588, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.