ZFIN ID: ZDB-FIG-070710-1
Chocron et al., 2007 - Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points. Developmental Biology   305(2):577-588 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: 20-25 somites to Long-pec
PHENOTYPE:
Fish:
Observed In:
Stage Range: 20-25 somites to Long-pec

Fig. 1 Laterality defects in laf/alk8 mutant embryos. (A–C) Wild-type sibling (A) and laf/alk8 mutant (B) embryo at 30 hpf stained for cmlc2 expression to reveal positioning of the heart and quantification of the results (C). (D–G) Wild-type sibling (D) and laf/alk8 mutant (E, F) embryos at 50 hpf stained for foxa3 expression to reveal the positioning of the liver (l), pancreas (p) and gut (g) and quantification of the results (G). (H–K) Wild-type sibling (H) and laf/alk8 mutant (I, J) embryos at 22 somite stage stained for lefty1 expression in the dorsal diencephalon and quantification of the results (K). All pictures are of dorsal views with anterior to the top (M, middle; L, left; R, right; B, bilateral; A, absent).

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
foxa3 acvr1ltm110b/+(TU) standard conditions Long-pec gut ISH
Long-pec liver ISH
Long-pec pancreas ISH
acvr1ltm110b/tm110b(TU) standard conditions Long-pec gut ISH
Long-pec liver ISH
Long-pec pancreas ISH
lft1 acvr1ltm110b/+(TU) standard conditions 20-25 somites diencephalon ISH
acvr1ltm110b/tm110b(TU) standard conditions 20-25 somites diencephalon ISH
myl7 acvr1ltm110b/+(TU) standard conditions Prim-15 heart tube ISH
acvr1ltm110b/tm110b(TU) standard conditions Prim-15 heart tube ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
acvr1ltm110b/tm110b(TU) standard conditions 20-25 somites diencephalon bilateral, abnormal
Prim-15 atrium increased width, abnormal
Prim-15 atrium position, abnormal
Long-pec heart looping arrested, abnormal
Acknowledgments:
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Reprinted from Developmental Biology, 305(2), Chocron, S., Verhoeven, M.C., Rentzsch, F., Hammerschmidt, M., and Bakkers, J., Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points, 577-588, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.