FIGURE

Fig. 4

ID

ZDB-FIG-070613-37

Publication

Chocron et al., 2007 - Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points

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Fig. 4

Bmp4 expression at early and late somite stages. Lateral view of a 10-somite stage embryo showing Bmp4 expression in an anterior and posterior expression domain (A). Boxed area shown in panel A is enlarged in panel B and shows bmp4 expression in and around Kupffer's vesicle (arrow). At the 20–22 somite stage (C), bmp4 expression is confined to the cardiac field and LPM where it is stronger on the left compared with the right side. Injection of a spw MO results in a down-regulation of bmp4 expression in the left LPM (D). Lateral views with anterior to the right (A, B) and dorsal views with anterior to the top (C, D). L, left; R, right.

Expression Data

Gene:	bmp4
Fish:	WT WT + MO1-spaw
Knockdown Reagent:	MO1-spaw
Anatomical Terms:	heart rudiment Kupffer's vesicle lateral plate mesoderm polster tail bud
Stage Range:	10-13 somites to 20-25 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 305(2), Chocron, S., Verhoeven, M.C., Rentzsch, F., Hammerschmidt, M., and Bakkers, J., Zebrafish Bmp4 regulates left-right asymmetry at two distinct developmental time points, 577-588, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.