FIGURE

Fig. 2

ID

ZDB-FIG-070502-19

Publication

Zhang et al., 2007 - The characterization of zebrafish antimorphic mib alleles reveals that Mib and Mind bomb-2 (Mib2) function redundantly

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Fig. 2

The mib^ta52b and mib^m132 antimorphic phenotypes are caused by Mib^ta52b and Mib^m132 proteins, respectively. (A–C) Control (or mib-m2-injected) wt (or mib^ta52b) embryos probed with (A) deltaC at 10ss, dorsal view; (B) huC at 10ss, dorsal view, and (C) her4 at 22hpf, (a–d) head region, dorsal view and (a2–d2) trunk region, lateral view. (D–F) 3dpf tail pigment phenotype in panel D (a) control mib^ta52b or (b, c) mib-m2-injected mib^ta52b embryos, (E) mib-m1-injected mib^ta52b embryos and (F) (a) control mib^m132 or (b) mib-m2-injected mib^m132 embryos. All are lateral views. (G) her4 expression at 22hpf in control or mib-m2-injected mib^m132 embryos, (a–b) head region, dorsal view and (a′–b′) trunk region, lateral view. All are head to the left.

Expression Data

Genes:	dlc elavl3 her4.1
Fish:	WT mib1^m132/m132 mib1^m132/m132 + MO4-mib1 mib1^ta52b/ta52b mib1^ta52b/ta52b + MO4-mib1 WT + MO4-mib1
Knockdown Reagent:	MO4-mib1
Anatomical Terms:	diencephalon hindbrain midbrain neural keel neural tube presumptive neural retina segmental plate
Stage Range:	10-13 somites to 26+ somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mib1^m132/m132 mib1^m132/m132 + MO4-mib1 mib1^ta52b/ta52b mib1^ta52b/ta52b + MO3-mib1 mib1^ta52b/ta52b + MO4-mib1
Knockdown Reagents:	MO3-mib1 MO4-mib1
Observed In:	post-vent region post-vent region melanocyte
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 305(1), Zhang, C., Li, Q., Lim, C.H., Qiu, X., and Jiang, Y.J., The characterization of zebrafish antimorphic mib alleles reveals that Mib and Mind bomb-2 (Mib2) function redundantly, 14-27, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.