FIGURE

Fig. 4

ID

ZDB-FIG-070502-21

Publication

Zhang et al., 2007 - The characterization of zebrafish antimorphic mib alleles reveals that Mib and Mind bomb-2 (Mib2) function redundantly

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Fig. 4

mib2 knock-down in mib^tfi91 embryos phenocopies mib^ta52b and mib^m132. (A) her4 expression in (a–a″) control mib^ta52b, (b–b″) mib mRNA-injected mib^ta52b, and (c–c″) mib2 mRNA-injected mib^ta52b embryos at 22hpf; (a–c) head region, dorsal view; (a′–c′) trunk region, and (a″–c″) tail region around cloaca, both lateral view. (B) 3dpf tail pigmentation of (a) control mib^ta52b and (b) mib mRNA-injected mib^ta52b embryos, lateral view. (C–E) Phenotypic analysis in control or mib2-m3-injected mib^tfi91 embryos. (C) islet-1 expression at 20ss, dorsal view; (D) her4 expression at 22hpf; (a–d) head region, dorsal view; (a′–d′) trunk region, lateral view and (E) 3dpf tail pigmentation, lateral view.

Expression Data

Genes:	her4.1 isl1a
Fish:	WT mib1^ta52b/ta52b mib1^tfi91/tfi91 WT + MO1-mib2 mib1^tfi91/tfi91 + MO1-mib2
Knockdown Reagent:	MO1-mib2
Anatomical Terms:	diencephalon hindbrain midbrain neural tube neuron presumptive neural retina
Stage:	26+ somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mib1^tfi91/tfi91 mib1^tfi91/tfi91 + MO1-mib2
Knockdown Reagent:	MO1-mib2
Observed In:	post-vent region post-vent region melanocyte
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 305(1), Zhang, C., Li, Q., Lim, C.H., Qiu, X., and Jiang, Y.J., The characterization of zebrafish antimorphic mib alleles reveals that Mib and Mind bomb-2 (Mib2) function redundantly, 14-27, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.