ZFIN: Gene: ptc1

ZFIN ID: ZDB-GENE-980526-44

Gene Name:patched 1

Gene Symbol: ptc1

Previous Names: etID309849.2(1) , ptc-1, blw(1) , blowout(1)
Nomenclature History

GENE EXPRESSION:(current status)

All expression data:	94 figure(s) from 65 publications
Directly submitted expression data:	6 figure(s) (12 images) from Thisse et al., 2005 [eu467]
Wild Type Stages, Structures:	Gastrula:90%-epiboly (9.00h-10.00h) to Larval:Day 6 (144.00h-168.00h)
	adaxial cell, axis ... (all 40)
Curated microarray expression:	GEO (1)

MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s): 9 genotypes
Allele(s): hu1602, tc294z

Phenotype: (current status)

Data:	11 figures from 5 publications
Observed in:	axon, brain, eye, fast muscle cell, lens ... (all 25)

Knockdown reagents: MO1-ptc1 (1) , MO2-ptc1 (1) , MO3-ptc1 (1)

GENE PRODUCTS:

Gene Ontology

Ontology GO Term
Biological Process cardioblast differentiation (more)

Cellular Component integral to membrane (more)

Molecular Function hedgehog receptor activity (more)

All GO Terms (10)

Ontology	GO Term
Biological Process	cardioblast differentiation (more)
Cellular Component	integral to membrane (more)
Molecular Function	hedgehog receptor activity (more)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

ptc1 Contained in	[BAC] CH211-226H23 (1) (order this)
ptc1 Encodes	[EST] eu467 (1) [cDNA] MGC:162571 (1) (order this)

Type	Accession #	Length (bp/aa)
RNA	RefSeq:NM_130988 (1)	3672 bp
Genomic	GenBank:BX649493 (1)	175551 bp
Polypeptide	UniProtKB:Q98864 (1)	1220 aa
Sequence Clusters	UniGene:75755 (1)
All Sequence Information (10)

OTHER ptc1 GENE / MARKER PAGES:

Entrez Gene:30181 (1)

VEGA:OTTDARG00000019874 (1)

Ensembl(Zv8):ENSDARG00000055026 (1)

MAPPING INFORMATION:

LG: 2 Details

View Map: Merged Individual Panels

ORTHOLOGY:

CITATIONS (133)