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General Information
ZIRC
ZFIN ID: ZDB-FISH-150901-22118
Fish name: ptch2tc294z/tc294z
Genotype: ptch2tc294z/tc294z
Targeting Reagent: none
HUMAN DISEASE MODELED by ptch2tc294z/tc294z
Human Disease Conditions Citations
coloboma standard conditions Gordon et al., 2018
GENE EXPRESSION
Gene expression in ptch2tc294z/tc294z
Reporter gene expression No data available
PHENOTYPE
Phenotype in ptch2tc294z/tc294z
Phenotype Conditions Figures
cell population proliferation occurrence, normal chemical treatment: 5-bromo-2'-deoxyuridine Fig. 3 with image from Lee et al., 2008
eye morphology, abnormal standard conditions Fig. 1 with imageFig. 2 with imageFig. 7 with image from Gordon et al., 2018
eye protruding into diencephalon, abnormal standard conditions Fig. 2 from Karlstrom et al., 1996
eye structure, abnormal standard conditions Fig. 2 from Karlstrom et al., 1996
lens development in camera-type eye process quality, normal standard conditions Fig. 1 with image from Lee et al., 2008
mandibular arch skeleton malformed, abnormal standard conditions Fig. S1 with image from Lee et al., 2008
optic cup pax2a expression increased amount, abnormal standard conditions Fig. 6 with image from Gordon et al., 2018
optic cup pax2a expression increased distribution, abnormal standard conditions Fig. 6 with image from Gordon et al., 2018
optic cup cell migration process quality, abnormal standard conditions Fig. 3 with imageFig. 4 with imageFig. S1 with image from Gordon et al., 2018
optic fissure closure incomplete, abnormal standard conditions Fig. 1 with imageFig. 7 with image from Gordon et al., 2018
Fig. 1 with imageFig. 2 with imageFig. 4 with image from Lee et al., 2008
optic fissure pax2a expression increased amount, abnormal standard conditions Fig. 6 with image from Gordon et al., 2018
optic fissure pax2a expression increased distribution, abnormal standard conditions Fig. 6 with image from Gordon et al., 2018
optic fissure morphology, abnormal standard conditions Fig. 2 with imageFig. 7 with image from Gordon et al., 2018
optic fissure open, abnormal standard conditions Fig. 2 with imageFig. 7 with image from Gordon et al., 2018
optic fissure cell migration process quality, abnormal standard conditions Fig. S1 with image from Gordon et al., 2018
optic stalk increased size, abnormal standard conditions Fig. 4 with imageFig. 5 with image from Lee et al., 2008
optic stalk kinked, abnormal standard conditions Fig. 4 with image from Lee et al., 2008
optic stalk mislocalised, abnormal standard conditions Fig. 4 with imageFig. 5 with image from Lee et al., 2008
optic stalk cell migration process quality, abnormal standard conditions Fig. 3 with imageFig. 4 with image from Gordon et al., 2018
optic vesicle decreased size, abnormal standard conditions Fig. 5 with image from Lee et al., 2008
optic vesicle pax2a expression increased amount, abnormal standard conditions Fig. 6 with image from Gordon et al., 2018
optic vesicle pax2a expression increased distribution, abnormal standard conditions Fig. 6 with image from Gordon et al., 2018
optic vesicle cell migration process quality, abnormal standard conditions Fig. 3 with imageFig. 4 with imageFig. S1 with image from Gordon et al., 2018
photoreceptor outer segment layer protruding, abnormal standard conditions Fig. 2 with image from Lee et al., 2008
presumptive neural retina decreased size, abnormal standard conditions Fig. 5 with image from Lee et al., 2008
reproductive process process quality, normal standard conditions Fig. S1 with image from Lee et al., 2008
retina protruding, abnormal standard conditions Fig. 1 with imageFig. 2 with image from Lee et al., 2008
retina basal lamina morphology, normal chemical treatment: 5-bromo-2'-deoxyuridine Fig. 3 with image from Lee et al., 2008
retina development in camera-type eye process quality, normal standard conditions Fig. 1 with image from Lee et al., 2008
retinal ganglion cell axon disorganized, abnormal standard conditions Fig. 2 with image from Lee et al., 2008
retinal ganglion cell axon ipsilateral to eye, abnormal standard conditions Fig. 1 from Karlstrom et al., 1996
retinal ganglion cell cell body mislocalised, abnormal standard conditions Fig. 1 from Karlstrom et al., 1996
retinal ganglion cell axon guidance process quality, abnormal standard conditions Fig. 1 from Karlstrom et al., 1996
retinal pigmented epithelium protruding, abnormal standard conditions Fig. 1 with image from Lee et al., 2008
skeletal system development disrupted, abnormal standard conditions Fig. S1 with image from Lee et al., 2008
ventral mandibular arch protruding, abnormal standard conditions Fig. S1 with image from Lee et al., 2008
whole organism curved, abnormal standard conditions Fig. S1 with image from Lee et al., 2008
whole organism decreased size, abnormal standard conditions Fig. S1 with image from Lee et al., 2008

CITATIONS  (7)