Research
General Information
ZIRC
ZFIN: Gene: eng2a
ZFIN ID: ZDB-GENE-980526-167

Gene Name:engrailed 2a
Gene Symbol: eng2a
Previous Names: Zf-en(1) , eng2(1)


GENE EXPRESSION:(current status)
All expression data: 56 figure(s) from 39 publications
Directly submitted expression data: 7 figure(s) (15 images) from Thisse et al., 2005 [eu759]
Wild Type Stages, Structures: Cleavage:64-cell (2.00h-2.25h) to Larval:Day 5 (120.00h-144.00h, 3.9mm, 6 teeth)
  constrictor dorsalis, dilator operculi ... (all 14)
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Mutant line(s):   1 genotype
Allele(s):   Df(LG07:ccne,eng2a,shha)b240
Phenotype: (current status)
Knockdown reagent: MO1-eng2a (1)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Molecular Function DNA binding (more)
Biological Process anterior/posterior pattern formation (more)
Cellular Component nucleus
All GO Terms (11)

Protein Families, Domains and Sites:
  • InterPro:IPR000047 (1)
  • InterPro:IPR000747 (1)
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR012287 (1)
  • InterPro:IPR015703 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR019549 (1)
  • InterPro:IPR019737 (1)
  • InterPro:IPR020479 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS00033 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF10525 (1)
  • Gene Product Description


    ANTIBODIES:
    Ab-eng (13)


    SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    eng2a Contained in [BAC] CH211-105D1 (1)    (order this) , CH211-150E22 (1)    (order this)
    eng2a Encodes [EST] eu759 (1)
    [cDNA] MGC:193941 (1) , MGC:193943 (1)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131044 (1) 2607 bp
    Genomic GenBank:CU041319 (1) 174262 bp
    Polypeptide UniProtKB:B3DGA1 (1) 265 aa
    Sequence Clusters UniGene:75073 (1)
    All Sequence Information (23)

    OTHER  eng2a  GENE / MARKER PAGES:

  • Entrez Gene:30243 (1)
  • Ensembl(Zv8):ENSDARG00000026599 (1)

  • MAPPING INFORMATION:
      LG:  7    Details   View Map: Merged  Individual Panels

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA NT CL
    Zebrafish eng2a  7
    Human EN2  7 (q36)
  • OMIM:131310
  • Entrez Gene:2020
  • Mouse En2  5 (15.00 cM)
  • MGI:95390
  • Entrez Gene:13799
  • Orthology Details

    CITATIONS   (78)