ZFIN ID: ZDB-GENE-980526-40
Gene Name: engrailed homeobox 2b
Gene Symbol: en2b
Sequence Ontology ID : SO:0000704

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Previous Names: en3 (1), eng2b, eng3 (1), engrailed 3

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(Including Attributions)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have sequence-specific DNA binding activity; involved in cell fate specification, midbrain development, and midbrain-hindbrain boundary development; predicted to localize to the nucleus;  ...
GENE EXPRESSION
All Expression Data: 40 figures from 24 publications
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2004 [IMAGE:7141696]
Wild-type Stages, Structures: Gastrula:90%-epiboly (9.0h-10.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE No data available
DISEASE ASSOCIATED WITH en2b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH en2b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process anterior/posterior pattern specification (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000047 (1)
  • InterPro:IPR000747 (1)
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR019549 (1)
  • InterPro:IPR019737 (1)
  • InterPro:IPR020479 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS00033 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF10525 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA eng2b-001 (1) 1825
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM en2b No data available
    MARKER RELATIONSHIPS
    en2bContained in: [BAC] DKEY-265A7 (1) (order this)
    en2bEncodes: [EST] IMAGE:7141696 (1) (order this)
    [cDNA] MGC:86574 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131040 (1) 1823bp
    Genomic GenBank:BX510360 (1) 213323bp Blast at MegaBLAST
    Polypeptide UniProtKB:A3KPY2 (1) 261aa
    Sequence Clusters UniGene:498 (1)
    Sequence Information (all 16)
    OTHER en2b GENE PAGES
  • Alliance (1)
  • Gene:30238 (1)
  • VEGA:OTTDARG00000018409 (1)
  • Ensembl(GRCz11):ENSDARG00000038868 (2)
  • ORTHOLOGY for en2b (Chr: 2)
    CITATIONS (82)