ZFIN ID: ZDB-GENE-980526-167
Gene Name: engrailed homeobox 2a
Gene Symbol: en2a
Sequence Ontology ID : SO:0000704

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Previous Names: eng2 (1), eng2a, Zf-en (1)

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 94 figures from 65 publications
Directly Submitted Expression Data: 7 figures (15 images) from Thisse et al., 2005 [eu759]
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  adaxial cell, cerebellum, constrictor dorsalis, floor plate neural tube (all 32) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-en2a (1)
PHENOTYPE
Data: Fig. 1 from Scholpp et al., 2001
Observed in: optic tectum
DISEASE ASSOCIATED WITH en2a HUMAN ORTHOLOGNo data available
GENE ONTOLOGY
Ontology GO Term
Biological Process anterior/posterior pattern specification (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000047
  • InterPro:IPR000747
  • InterPro:IPR001356
  • InterPro:IPR009057
  • InterPro:IPR017970
  • InterPro:IPR019549
  • InterPro:IPR019737
  • InterPro:IPR020479
  • PROSITE:PS00027
  • PROSITE:PS00033
  • PROSITE:PS50071
  • Pfam:PF00046
  • Pfam:PF10525
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA eng2a-001 (1) 2910
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab1-eng (1), Ab2-eng (1)
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM en2a
    Tg(-8en2a:EGFP), Tg(-10en2a:EGFP), Tg1(en2a:EGFP), Tg2(en2a:EGFP), Tg3(en2a:EGFP) (all 18) expand
    MARKER RELATIONSHIPS
    en2aContained in: [BAC] CH211-105D1 (1) (order this), CH211-150E22 (1) (order this)
    en2aEncodes: [EST] eu759 (1)
    [cDNA] MGC:193941 (1), MGC:193943 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131044 (1) 2901bp
    Genomic GenBank:CU041319 (1) 174262bp
    Select Tool
    Polypeptide UniProtKB:B3DGA1 265aa
    Sequence Clusters UniGene:162132 (1)
    Sequence Information (all 28)
    OTHER en2a GENE PAGES
  • Gene:30243 (1)
  • VEGA:OTTDARG00000018405 (1)
  • Ensembl(GRCz10):ENSDARG00000026599 (1)
  • ORTHOLOGY for en2a (Chr: 7)
    CITATIONS (143)