ZFIN ID: ZDB-GENE-980526-167
Gene Name: engrailed homeobox 2a
Gene Symbol: en2a
Sequence Ontology ID : SO:0000704

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Previous Names: eng2 (1), eng2a, Zf-en (1)

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have sequence-specific DNA binding activity; involved in several processes, including apoptotic process involved in morphogenesis, cell fate specification, and nervous system  ...
GENE EXPRESSION
All Expression Data: 98 figures from 69 publications
Directly Submitted Expression Data: 7 figures (15 images) from Thisse et al., 2005 [eu759]
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE
Data: Fig. 1 from Scholpp et al., 2001
Observed in:
DISEASE ASSOCIATED WITH en2a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH en2a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process anterior/posterior pattern specification (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000047 (1)
  • InterPro:IPR000747 (1)
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR019549 (1)
  • InterPro:IPR019737 (1)
  • InterPro:IPR020479 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS00033 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF10525 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA eng2a-001 (1) 2910
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM en2a
    MARKER RELATIONSHIPS
    en2aContained in: [BAC] CH211-105D1 (1) (order this), CH211-150E22 (1) (order this)
    en2aEncodes: [EST] eu759 (1)
    [cDNA] MGC:193941 (1), MGC:193943 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131044 (1) 2607bp
    Genomic GenBank:CU041319 (1) 174262bp
    Select Tool
    Polypeptide UniProtKB:B3DGA1 (1) 265aa
    Sequence Clusters UniGene:162132 (1)
    Sequence Information (all 28)
    OTHER en2a GENE PAGES
  • Alliance (1)
  • Gene:30243 (1)
  • VEGA:OTTDARG00000018405 (1)
  • ORTHOLOGY for en2a (Chr: 7)
    CITATIONS (153)