ZFIN ID: ZDB-GENE-980526-368
Gene Name: apolipoprotein Eb
Gene Symbol: apoeb
Previous Names: ApoE-2 (1), apoe, cb82 (1), hm:zeh1311, wu:fa03d06 (1), wu:fa97a11 (1), wu:fc95h12 (1), wu:fj54e06 (1), zeh1311
Location: Chr: 16   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 54 figures from 23 publications
Directly Submitted Expression Data: 7 figures (19 images) from Thisse et al., 2005 [eu173]
  7 figures (8 images) from Thisse et al., 2001 [cb82]
Wild-type Stages, Structures: Blastula:128-cell (2.25h-2.5h) to Adult (90d-730d, breeding adult)
  anal fin, apical ectodermal ridge, apical ectodermal ridge dorsal fin, apical ectodermal ridge pectoral fin bud (all 58) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: apoebscu3/scu3
Knockdown reagents: TALEN1-apoeb (1)

Allele Type Mutagen Suppliers
scu3 Indel TALEN
PHENOTYPE No data available
DISEASE ASSOCIATED WITH apoeb HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Alzheimer's disease Alzheimer disease-2 104310
sea-blue histiocyte syndrome Sea-blue histiocyte disease 269600
age related macular degeneration {?Macular degeneration, age-related} 603075
Lipoprotein glomerulopathy 611771
Hyperlipoproteinemia, type III
{Myocardial infarction susceptibility}
GENE ONTOLOGY
Ontology GO Term
Biological Process lipid transport (more)
Cellular Component extracellular region (more)
Molecular Function lipid binding (more)
GO Terms (all 34)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000074 (1)
  • Pfam:PF01442 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA apoeb-001 (1) 1521
    apoeb-002 (1) 846
    ncRNA apoeb-003 (1) 882
    apoeb-004 (1) 897
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM apoeb
    Tg(apoeb:LY-EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    apoeb Contained in: [BAC] DKEY-7F3 (1) (order this)
    apoeb Encodes: [EST] cb82 (1) (order this), eu173 (1), fa03d06 (1), fa97a11 (1), fc95h12 (1), fj54e06 (1), zeh1311
    [cDNA] MGC:56515 (1) (order this), MGC:77232 (1) (order this), MGC:171895 (1) (order this)
    apoeb Has Artifact: [EST] fa96d02
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131098 (1) 1345 bp
    Genomic GenBank:BX004983 (1) 234489 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A8KBA6 (1) 281 aa
    Sequence Clusters UniGene:23502 (1)
    Sequence Information (all 35)
    OTHER apoeb GENE PAGES
  • Gene:30314 (1)
  • VEGA:OTTDARG00000021059 (1)
  • Ensembl(Zv9):ENSDARG00000040295 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish apoeb 16  
    Human APOE 19 (19q13.2)
  • OMIM:107741
  • Gene:348
  • Mouse Apoe 7 ( 9.94 cM)
  • MGI:88057
  • Gene:11816
  • Orthology Details
    CITATIONS (63)