ZFIN ID: ZDB-GENE-980526-368
Gene Name: apolipoprotein Eb
Gene Symbol: apoeb
Previous Names: apoe, ApoE-2 (1), cb82 (1), hm:zeh1311, wu:fa03d06 (1), wu:fa97a11 (1), wu:fc95h12 (1), wu:fj54e06 (1), zeh1311
Location: Chr: 16   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 47 figures from 20 publications
Directly Submitted Expression Data: 7 figures (19 images) from Thisse et al., 2005 [eu173]
  7 figures (8 images) from Thisse et al., 2001 [cb82]
Wild-type Stages, Structures: Blastula:128-cell (2.25h-2.5h) to Adult (90d-730d, breeding adult)
  anal fin, apical ectodermal ridge, apical ectodermal ridge dorsal fin, apical ectodermal ridge pectoral fin bud (all 49) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Alzheimer disease-2 104310
Hyperlipoproteinemia, type III
Lipoprotein glomerulopathy 611771
Sea-blue histiocyte disease 269600
{?Macular degeneration, age-related} 603075
{Myocardial infarction susceptibility}
GENE ONTOLOGY
Ontology GO Term
Biological Process lipid transport (more)
Cellular Component extracellular region (more)
Molecular Function lipid binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000074 (1)
  • Pfam:PF01442 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA apoeb-001 (1) 1521
    apoeb-002 (1) 846
    ncRNA apoeb-003 (1) 882
    apoeb-004 (1) 897
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM apoeb
    Tg(apoeb:LY-EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    apoeb Contained in: [BAC] DKEY-7F3 (1)
    apoeb Encodes: [EST] cb82 (1) (order this), eu173 (1), fa03d06 (1), fa97a11 (1), fc95h12 (1), fj54e06 (1), zeh1311
    [cDNA] MGC:56515 (1) (order this), MGC:77232 (1) (order this), MGC:171895 (1) (order this)
    apoeb Has Artifact: [EST] fa96d02
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131098 (1) 1345 bp
    Genomic GenBank:BX004983 (1) 234489 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A8KBA6 (1) 281 aa
    Sequence Clusters UniGene:23502 (1)
    Sequence Information (all 35)
    OTHER apoeb GENE PAGES
  • Gene:30314 (1)
  • VEGA:OTTDARG00000021059 (1)
  • Ensembl(Zv9):ENSDARG00000040295 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish apoeb 16  
    Human APOE 19 (19q13.2)
  • OMIM:107741
  • Gene:348
  • Mouse Apoe 7 ( 9.94 cM)
  • MGI:88057
  • Gene:11816
  • Orthology Details
    CITATIONS (57)