ZFIN ID: ZDB-GENE-980526-368
Gene Name: apolipoprotein Eb
Gene Symbol: apoeb
Previous Names: ApoE-2 (1), apoe, cb82 (1), hm:zeh1311, wu:fa03d06 (1), wu:fa97a11 (1), wu:fc95h12 (1), wu:fj54e06 (1), zeh1311
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 57 figures from 26 publications
Directly Submitted Expression Data: 7 figures (19 images) from Thisse et al., 2005 [eu173]
  7 figures (8 images) from Thisse et al., 2001 [cb82]
Wild-type Stages, Structures: Blastula:128-cell (2.25h-2.5h) to Adult (90d-730d, breeding adult)
  anal fin, apical ectodermal ridge, apical ectodermal ridge dorsal fin, apical ectodermal ridge pectoral fin bud (all 59) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa36120 Point Mutation Unknown Unknown ENU
scu3 Indel Unknown Unknown TALEN
Targeting reagents: TALEN1-apoeb (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH apoeb HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
age related macular degeneration {?Macular degeneration, age-related} 603075
Alzheimer's disease Alzheimer disease-2 104310
sea-blue histiocyte syndrome Sea-blue histiocyte disease 269600
{Myocardial infarction susceptibility}
Hyperlipoproteinemia, type III
Lipoprotein glomerulopathy 611771
GENE ONTOLOGY
Ontology GO Term
Biological Process lipid transport (more)
Cellular Component extracellular region (more)
Molecular Function lipid binding (more)
GO Terms (all 34)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000074 (1)
  • Pfam:PF01442 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA apoeb-001 (1) 1521
    apoeb-002 (1) 846
    ncRNA apoeb-003 (1) 882
    apoeb-004 (1) 897
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM apoeb
    Tg(apoeb:LY-EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    apoebContained in: [BAC] DKEY-7F3 (1) (order this)
    apoebEncodes: [EST] cb82 (1) (order this), eu173 (1), fa03d06 (1), fa97a11 (1), fc95h12 (1), fj54e06 (1), zeh1311
    [cDNA] MGC:56515 (1) (order this), MGC:77232 (1) (order this), MGC:171895 (1) (order this)
    apoebHas Artifact: [EST] fa96d02
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131098 (1) 1345bp
    Genomic GenBank:BX004983 (1) 234489bp Blast at MegaBLAST
    Polypeptide UniProtKB:A8KBA6 (1) 281aa
    Sequence Clusters UniGene:23502 (1)
    Sequence Information (all 35)
    OTHER apoeb GENE PAGES
  • Gene:30314 (1)
  • VEGA:OTTDARG00000021059 (1)
  • Ensembl(GRCz10):ENSDARG00000040295 (1)
  • ORTHOLOGY for apoeb (Chr: 16)
    Species Symbol Chromosome Accession # Evidence
    Human APOE 19
  • Gene:348
  • OMIM:107741
  • HGNC:613
  • Amino acid sequence comparison (4)
    Conserved genome location (synteny) (3)
    Mouse Apoe 7
  • MGI:88057
  • Gene:11816
  • Amino acid sequence comparison (3)
    Download Curated Orthology
    CITATIONS (76)