ZFIN ID: ZDB-GENE-980526-167
Gene Name: engrailed homeobox 2a
Gene Symbol: eng2a
Previous Names: eng2 (1), Zf-en (1)
Location: Chr: 7   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 85 figures from 59 publications
Directly Submitted Expression Data: 7 figures (15 images) from Thisse et al., 2005 [eu759]
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  adaxial cell, cerebellum, constrictor dorsalis, floor plate neural tube (all 19) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 1 genotype
Alleles: b240
Knockdown reagents: MO1-eng2a (1)
PHENOTYPE
Data: Fig. 1 from Scholpp et al., 2001
Observed in: optic tectum
GENE ONTOLOGY
Ontology GO Term
Biological Process anterior/posterior pattern specification (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000047 (1)
  • InterPro:IPR000747 (1)
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR019549 (1)
  • InterPro:IPR019737 (1)
  • InterPro:IPR020479 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS00033 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF10525 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA eng2a-001 (1) 2887
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-eng (1), Ab2-eng (1)
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM eng2a
    Tg(-8eng2a:EGFP), Tg(-10eng2a:EGFP), Tg1(eng2a:EGFP), Tg2(eng2a:EGFP), Tg3(eng2a:EGFP) (all 18) expand
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    eng2a Contained in: [BAC] CH211-105D1 (1) (order this), CH211-150E22 (1) (order this)
    eng2a Encodes: [EST] eu759 (1)
    [cDNA] MGC:193941 (1), MGC:193943 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131044 (1) 2901 bp
    Genomic GenBank:CU041319 (1) 174262 bp
    Select Tool
    Polypeptide UniProtKB:B3DGA1 (1) 265 aa
    Sequence Clusters UniGene:75073 (1)
    Sequence Information (all 27)
    OTHER eng2a GENE PAGES
  • Gene:30243 (1)
  • VEGA:OTTDARG00000018405 (1)
  • Ensembl(Zv9):ENSDARG00000026599 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA NT CL
    Zebrafish eng2a 7  
    Human EN2 7 (7q36)
  • OMIM:131310
  • Gene:2020
  • Mouse En2 5 ( 13.94 cM)
  • MGI:95390
  • Gene:13799
  • Orthology Details
    CITATIONS (128)