ZFIN ID: ZDB-TALEN-180718-1
TALEN Name: TALEN1-dgcr8
Target: dgcr8 (1)
Source:
Target Sequence 1:
5' - TAGCACAAAAACCGAAAC - 3'
   
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Target Sequence 2:
5' - TTGTAATTGTTTAATTGC - 3'
   
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  (Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.)
TARGET LOCATIONS
No data available
CONSTRUCTS WITH SEQUENCES FROM TALEN1-dgcr8 No data available
GENOMIC FEATURES CREATED WITH TALEN1-dgcr8
Genomic Feature Affected Genomic Regions    
zf1064 dgcr8    
GENE EXPRESSION
Gene expression in Wild Types + TALEN1-dgcr8 No data available
PHENOTYPE
Phenotype resulting from TALEN1-dgcr8
No data available

Phenotype of all Fish created by or utilizing TALEN1-dgcr8
Phenotype Fish Conditions Figures
whole organism decreased size, abnormal dgcr8zf1064/zf1064 standard conditions Fig. 1 from Liu et al., 2017
whole organism decreased life span, abnormal dgcr8zf1064/zf1064 standard conditions Fig. 1 from Liu et al., 2017
blood circulation arrested, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 5 from Liu et al., 2017
myeloid cell spi1b expression absent, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 6 from Liu et al., 2017
epiboly process quality, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 5 from Liu et al., 2017
gene silencing by miRNA decreased occurrence, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 4 from Liu et al., 2017
heart contraction arrested, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 5 from Liu et al., 2017
primary miRNA processing decreased occurrence, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 4 from Liu et al., 2017
whole organism mir25 expression decreased amount, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 4 from Liu et al., 2017
brain decreased size, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 5 from Liu et al., 2017
endoderm sox17 expression decreased amount, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 6 from Liu et al., 2017
whole organism mir21-1 expression decreased amount, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 4 from Liu et al., 2017
otic placode pax2a expression spatial pattern, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 6 from Liu et al., 2017
embryo development delayed, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 5 from Liu et al., 2017
brain morphology, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 5 from Liu et al., 2017
midbrain hindbrain boundary neural rod pax2a expression decreased amount, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 6 from Liu et al., 2017
presumptive dorsal mesoderm chrd expression decreased distribution, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 6 from Liu et al., 2017
cardioblast migration to the midline involved in heart field formation decreased occurrence, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 6 from Liu et al., 2017
endoderm sox32 expression decreased amount, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 6 from Liu et al., 2017
presumptive dorsal mesoderm gsc expression decreased distribution, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 6 from Liu et al., 2017
whole organism anterior-posterior axis increased length, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 5 from Liu et al., 2017
whole organism dorsal-ventral axis decreased size, abnormal dgcr8zf1064/zf1064 ; zf1065Tg ; ihb7Tg standard conditions Fig. 5 from Liu et al., 2017
OTHER TALEN1-dgcr8 TALEN PAGESNo links to external sites
CITATIONS (1)