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Research
General Information
ZIRC
ZFIN ID: ZDB-PERS-971001-8
Boehm, Tom
Email: boehm@immunbio.mpg.de
URL: http://www.immunbio.mpg.de/
Affiliation: Boehm Lab
Address: Department of Developmental Immunology Max-Planck-Institute for Immunobiology Stuebeweg 51 Freiburg, D-79108 Germany
Country: Germany
Phone: 49-761-510-8328
Fax: 49-761-510-8323
Orcid ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Tenno, M., Kojo, S., Lawir, D.F., Hess, I., Shiroguchi, K., Ebihara, T., Endo, T.A., Muroi, S., Satoh, R., Kawamoto, H., Boehm, T., Taniuchi, I. (2018) Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors. The Journal of experimental medicine. 215(2):595-610
Lawir, D.F., Iwanami, N., Schorpp, M., Boehm, T. (2017) A missense mutation in zbtb17 blocks the earliest steps of T cell differentiation in zebrafish. Scientific Reports. 7:44145
Iwanami, N., Hess, I., Schorpp, M., Boehm, T. (2017) Studying the adaptive immune system in zebrafish by transplantation of hematopoietic precursor cells. Methods in cell biology. 138:151-161
Iwanami, N., Sikora, K., Richter, A.S., Mönnich, M., Guerri, L., Soza-Ried, C., Lawir, D.F., Mateos, F., Hess, I., O'Meara, C.P., Schorpp, M., Boehm, T. (2016) Forward Genetic Screens in Zebrafish Identify Pre-mRNA-Processing Pathways Regulating Early T Cell Development. Cell Reports. 17:2259-2270
Hess, I., Boehm, T. (2016) Stable multilineage xenogeneic replacement of definitive hematopoiesis in adult zebrafish. Scientific Reports. 6:19634
Swann, J.B., Weyn, A., Nagakubo, D., Bleul, C.C., Toyoda, A., Happe, C., Netuschil, N., Hess, I., Haas-Assenbaum, A., Taniguchi, Y., Schorpp, M., Boehm, T. (2014) Conversion of the thymus into a bipotent lymphoid organ by replacement of FOXN1 with its paralog, FOXN4. Cell Reports. 8:1184-97
Venkatesh, B., Lee, A.P., Ravi, V., Maurya, A.K., Lian, M.M., Swann, J.B., Ohta, Y., Flajnik, M.F., Sutoh, Y., Kasahara, M., Hoon, S., Gangu, V., Roy, S.W., Irimia, M., Korzh, V., Kondrychyn, I., Lim, Z.W., Tay, B.H., Tohari, S., Kong, K.W., Ho, S., Lorente-Galdos, B., Quilez, J., Marques-Bonet, T., Raney, B.J., Ingham, P.W., Tay, A., Hillier, L.W., Minx, P., Boehm, T., Wilson, R.K., Brenner, S., and Warren, W.C. (2014) Elephant shark genome provides unique insights into gnathostome evolution. Nature. 505(7482):174-179
Hess, I., Iwanami, N., Schorpp, M., and Boehm, T. (2013) Zebrafish model for allogeneic hematopoietic cell transplantation not requiring preconditioning. Proceedings of the National Academy of Sciences of the United States of America. 110(11):4327-32
Hess, I., and Boehm, T. (2012) Intravital Imaging of Thymopoiesis Reveals Dynamic Lympho-Epithelial Interactions. Immunity. 36(2):298-309
Iwanami, N., Mateos, F., Hess, I., Riffel, N., Soza-Ried, C., Schorpp, M., and Boehm, T. (2011) Genetic Evidence for an Evolutionarily Conserved Role of IL-7 Signaling in T Cell Development of Zebrafish. Journal of immunology (Baltimore, Md. : 1950). 186(12):7060-6
Soza-Ried, C., Hess, I., Netuschil, N., Schorpp, M., and Boehm, T. (2010) Essential role of c-myb in definitive hematopoiesis is evolutionarily conserved. Proceedings of the National Academy of Sciences of the United States of America. 107(40):17304-17308
Mönnich, M., Hess, I., Wiest, W., Bachrati, C., Hickson, I.D., Schorpp, M., and Boehm, T. (2010) Developing T lymphocytes are uniquely sensitive to a lack of topoisomerase III alpha. European journal of immunology. 40(9):2379-2384
Bajoghli, B., Aghaallaei, N., Hess, I., Rode, I., Netuschil, N., Tay, B.H., Venkatesh, B., Yu, J.K., Kaltenbach, S.L., Holland, N.D., Diekhoff, D., Happe, C., Schorpp, M., and Boehm, T. (2009) Evolution of genetic networks underlying the emergence of thymopoiesis in vertebrates. Cell. 138(1):186-197
Pannicke, U., Hönig, M., Hess, I., Friesen, C., Holzmann, K., Rump, E.M., Barth, T.F., Rojewski, M.T., Schulz, A., Boehm, T., Friedrich, W., and Schwarz, K. (2009) Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2. Nature Genetics. 41(1):101-105
Soza-Ried, C., Bleul, C.C., Schorpp, M., and Boehm, T. (2008) Maintenance of thymic epithelial phenotype requires extrinsic signals in mouse and zebrafish. Journal of immunology (Baltimore, Md. : 1950). 181(8):5272-5277
Schorpp, M., Bialecki, M., Diekhoff, D., Walderich, B., Odenthal, J., Maischein, H.M., Zapata, A.G., and Boehm, T. (2006) Conserved functions of ikaros in vertebrate lymphocyte development: genetic evidence for distinct larval and adult phases of T cell development and two lineages of B cells in zebrafish. Journal of immunology (Baltimore, Md. : 1950). 177(4):2463-2476
Boehm, T., Bleul, C.C., and Schorpp, M. (2003) Genetic dissection of thymus development in mouse and zebrafish. Immunological reviews. 195:15-27
Schorpp, M., Leicht, M., Nold, E., Hammerschmidt, M., Haas-Assenbaum, A., Wiest, W., and Boehm, T. (2002) A zebrafish orthologue (whnb) of the mouse nude gene is expressed in the epithelial compartment of the embryonic thymic rudiment. Mechanisms of Development. 118(1-2):179-185
Schlake, T., Schorpp, M., and Boehm, T. (2000) Formation of regulator/target gene relationships during evolution. Gene. 256(1-2):29-34
Schlake, T., Schorpp, M., Nehls, M., and Boehm, T. (1997) The nude gene encodes a sequence-specific DNA binding protein with homologs in organisms that lack an anticipatory immune system. Proceedings of the National Academy of Sciences of the United States of America. 94(8):3842-3847

NON-ZEBRAFISH PUBLICATIONS