ZFIN Image: Roberson et al., 2017, Fig. 4

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Figure Caption

Fig. 4

Specification of dbx1b⁺ dHb progenitors requires Shh signaling upstream of or parallel to Wnt signaling. At 36 hpf, (A,A′) cxcr4b and (B-C′) dbx1b transcripts are found in the developing dHb of (A,B,C) WT embryos, but not in the corresponding diencephalic region of (A′,B′,C′) smo mutants (arrowheads). Expression of (D-E′) shha and (F-G′) ptch1 is comparable in (D,E,F,G) WT embryos and (D′,E′,F′,G′) wls mutants. Sibling WT and homozygous wls mutant embryos are distinguished by the presence or absence of wls transcripts (Kuan et al., 2015). Dorsal (A-B′,D,D′,F,F′) and lateral (C,C′,E,E′,G,G′) views are shown. Scale bars: 30 µm.

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Acknowledgments

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