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ZIRC
ZFIN ID: ZDB-GENE-010614-1
Gene Name: chemokine (C-X-C motif), receptor 4b
Gene Symbol: cxcr4b
Sequence Ontology ID : SO:0001217

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Previous Names: drCXCR4b1 (1), cb403 (1), ody, odysseus, zgc:109863

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits G protein-coupled chemoattractant receptor activity. Involved in several processes, including gamete generation; nervous system development; and regulation of chemotaxis. Localizes to the  ...
GENE EXPRESSION
All Expression Data: 102 figures from 73 publications
Directly Submitted Expression Data: 6 figures (56 images) from Thisse et al., 2001 [cb403]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
t26035 Point Mutation Unknown Premature Stop
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH cxcr4b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    WHIM syndrome WHIM syndrome 193670
    Myelokathexis, isolated
    DISEASE ASSOCIATED WITH cxcr4b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of axon extension (more)
    Cellular Component plasma membrane (more)
    Molecular Function G protein-coupled chemoattractant receptor activity (more)
    GO Terms (all 39)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cxcr4b-201 (1) 1674
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    PLASMIDS
    Addgene
    MARKER RELATIONSHIPS
    cxcr4b Contained in: [Fosmid] CH1073-406F3 (1) (order this)
    cxcr4b Encodes: [EST] cb403 (1)
    [cDNA] MGC:109863 (1) (order this), MGC:192953 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131834 (1) 1651 bp
    Genomic GenBank:CU694482 (1) 35104 bp
    Select Tool
    Polypeptide UniProtKB:Q504H4 (1) 353 aa
    Sequence Clusters UniGene:75485 (1)
    Sequence Information (all 20)
    ORTHOLOGY for cxcr4b ( Chr: 9 )
    CITATIONS (191)