ZFIN ID: ZDB-GENE-980526-166
Gene Name: sonic hedgehog a
Gene Symbol: shha
Sequence Ontology ID : SO:0000704

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Previous Names: shh, fc83d08, sonic you, sonic-you (1), syu, vertebrate hedgehog homolog (1), vhh1 (1), wu:fc83d08 (1)

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 434 figures from 325 publications
Wild-type Stages, Structures: Blastula:256-cell (2.5h-2.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
shha_unspecified Unspecified Unknown Unknown
t4 Deficiency Unknown Unknown SPONTANEOUS
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tbq70 Unknown Unknown Unknown ENU
    tbx392 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tq252 Point Mutation Unknown Unknown
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • vcc8Gt Transgenic Insertion Intron 1 Unknown DNA_AND_TALEN
    Targeting reagents:
    PHENOTYPE
    Data: 30 figures from 19 publications
    Observed in:
    DISEASE ASSOCIATED WITH shha HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    holoprosencephaly 3 Holoprosencephaly 3 142945
    Schizencephaly 269160
    Microphthalmia with coloboma 5 611638
    Single median maxillary central incisor 147250
    DISEASE ASSOCIATED WITH shha VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process adenohypophysis development (more)
    Cellular Component membrane (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 67)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000320 (1)
  • InterPro:IPR001657 (1)
  • InterPro:IPR001767 (1)
  • InterPro:IPR003586 (1)
  • InterPro:IPR003587 (1)
  • InterPro:IPR006141 (1)
  • InterPro:IPR009045 (1)
  • InterPro:IPR036844 (1)
  • PROSITE:PS50817 (1)
  • Pfam:PF01079 (1)
  • Pfam:PF01085 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA shha-001 (1) 4551
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM shha
    MARKER RELATIONSHIPS
    shhaContained in: [BAC] CH211-105D1 (1) (order this), CH211-150E22 (1) (order this)
    shhaEncodes: [EST] fc83d08
    [cDNA] MGC:194075 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131063 (1) 2600bp
    Genomic GenBank:CU041319 (1) 174262bp
    Select Tool
    Polypeptide UniProtKB:A0A0B5JF88 (1) 418aa
    Sequence Clusters UniGene:115833 (1)
    Sequence Information (all 38)
    OTHER shha GENE PAGES
  • Alliance (1)
  • Gene:30269 (1)
  • VEGA:OTTDARG00000035495 (1)
  • ORTHOLOGY for shha (Chr: 7)
    CITATIONS (782)