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ZIRC
ZFIN ID: ZDB-GENE-980526-196
Gene Name: patched 1
Gene Symbol: ptch1
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: ptc2, lep, leprechaun

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(Including Attributions)
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have hedgehog receptor activity; involved in several processes, including animal organ development, intramembranous ossification, and negative regulation of muscle organ development;  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la016340Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa784 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa7141 Point Mutation Unknown Splice Site ENU
    sa9464 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17883 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21322 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21323 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34430 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tj222 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tq236 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH ptch1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    holoprosencephaly 7 Holoprosencephaly 7 610828
    nevoid basal cell carcinoma syndrome Basal cell nevus syndrome 109400
    Basal cell carcinoma, somatic 605462
    DISEASE ASSOCIATED WITH ptch1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cardioblast differentiation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function hedgehog receptor activity (more)
    GO Terms (all 10)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ptch1-202 (1) 4068
    ptch1-203 (1) 361
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ptch1 No data available
    MARKER RELATIONSHIPS
    ptch1Contained in: [BAC] CH211-248D20 (1) (order this), DKEY-72L19 (1) (order this), DKEY-185L9 (1) (order this)
    ptch1Encodes: [EST] eu578 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001305542 (1)
    Genomic GenBank:CR847548 (1) 249728bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1R8E2 (1) 1475aa
    Sequence Clusters UniGene:81263 (1)
    Sequence Information (all 19)
    ORTHOLOGY for ptch1 (Chr: 8)
    CITATIONS (116)