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Gene

wls

ID
ZDB-GENE-040426-2161
Name
Wnt ligand secretion mediator
Symbol
wls Nomenclature History
Previous Names
  • gpr177
  • id:ibd2010
  • sb:cb610
  • wu:fb36d04
  • wu:fb44d10
  • wu:fb50c06
  • zgc:64091
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable Wnt-protein binding activity. Acts upstream of or within several processes, including animal organ development; chondrocyte activation; and chondrocyte proliferation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in endomembrane system. Predicted to be integral component of organelle membrane. Is expressed in several structures, including central nervous system; head; inner ear; midbrain neural keel; and neural tube. Orthologous to human WLS (Wnt ligand secretion mediator).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
23 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
25 figures from 6 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wls Human Ortholog
No data available
Associated With wls Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR009551 Protein wntless
Domain Details Per Protein
Protein Length Protein wntless
UniProtKB:Q7T357 542
UniProtKB:F2Z4U3 542
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-wls polyclonal Guinea pig
  • IHC
  • WB
2
Ab1-wls polyclonal Rabbit
  • IHC
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations