Gene

mef2aa

ID
ZDB-GENE-990415-163
Name
myocyte enhancer factor 2aa
Symbol
mef2aa Nomenclature History
Previous Names
  • mef2a
  • etID309779.18 (1)
  • wu:fd19d02
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Exhibits transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including myofibril assembly; positive regulation of transcription by RNA polymerase II; and somitogenesis. Predicted to localize to nuclear chromatin. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Is expressed in cardiovascular system; myotome; nervous system; pharyngeal arch; and somite. Orthologous to human MEF2A (myocyte enhancer factor 2A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
20 figures from 12 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mef2aa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
coronary artery disease Alliance {Coronary artery disease, autosomal dominant, 1} 608320
Associated With mef2aa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002100 Transcription factor, MADS-box
Domain IPR022102 Holliday junction regulator protein family C-terminal
Domain IPR033896 MADS MEF2-like
Homologous_superfamily IPR036879 Transcription factor, MADS-box superfamily
Domain Details Per Protein
Protein Length Holliday junction regulator protein family C-terminal MADS MEF2-like Transcription factor, MADS-box Transcription factor, MADS-box superfamily
UniProtKB:Q1LXH5 488
UniProtKB:A0A0R4IRM3 460
UniProtKB:Q2MJS9 462
UniProtKB:Q1LXH6 458
UniProtKB:Q98868 460
UniProtKB:A0A2R8QIE4 459
UniProtKB:A0A2R8QMZ5 459
UniProtKB:Q1LXH4 524
UniProtKB:A0A2R8QU09 467
UniProtKB:Q1LXH3 487
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-mef2 polyclonal IgG Rabbit
  • IHC
AnaSpec
4
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations