ZFIN ID: ZDB-GENE-980526-253
Gene Name: myocyte enhancer factor 2ca
Gene Symbol: mef2ca
Sequence Ontology ID : SO:0000704

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Previous Names: mef2c, hoo, hoover, id:ibd5026, wu:fc05b06, zgc:64184, zgc:85726

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 36 figures from 21 publications
Directly Submitted Expression Data: 6 figures (15 images) from Thisse et al., 2004 [MGC:85726]
  2 figures (3 images) from Kudoh et al., 2001 [ibd5026]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b631 Point Mutation Unknown Missense
  • Zebrafish International Resource Center (ZIRC) (order this)
  • b1086 Point Mutation Exon 2 Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa2569 Point Mutation Unknown Splice Site ENU
    sa31806 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34988 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34989 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tn213 Point Mutation Donor Splice Site of Intron 7 Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 13 figures from 8 publications
    Observed in:
    DISEASE ASSOCIATED WITH mef2ca HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal dominant mental retardation 20 Chromosome 5q14.3 deletion syndrome 613443
    Mental retardation, stereotypic movements, epilepsy, and/or cerebral malformations 613443
    DISEASE ASSOCIATED WITH mef2ca VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of transcription by RNA polymerase II (more)
    Cellular Component nucleus (more)
    Molecular Function transcription regulatory region sequence-specific DNA binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002100 (1)
  • InterPro:IPR022102 (1)
  • InterPro:IPR033896 (1)
  • InterPro:IPR036879 (1)
  • PROSITE:PS00350 (1)
  • PROSITE:PS50066 (1)
  • Pfam:PF00319 (1)
  • Pfam:PF12347 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA mef2ca-001 6164
    mef2ca-002 3567
    mef2ca-003 3502
    mef2ca-004 393
    mef2ca-005 393
    mef2ca-006 318
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mef2ca No data available
    MARKER RELATIONSHIPS
    mef2caContained in: [BAC] CH73-215F7 (1) (order this)
    [Fosmid] CH1073-234A2 (1) (order this), CH1073-412J12 (1) (order this), CH1073-418F12 (1) (order this)
    mef2caEncodes: [EST] fc05b06, ibd5026 (order this)
    [cDNA] MGC:64184 (1) (order this), MGC:85726 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131312 (1) 4315bp
    Genomic GenBank:CU462873 (1) 95788bp
    Select Tool
    Polypeptide UniProtKB:Q6NSN7 (1) 491aa
    Sequence Clusters UniGene:3182 (1)
    Sequence Information (all 60)
    OTHER mef2ca GENE PAGES
  • Alliance (1)
  • Gene:30575 (1)
  • VEGA:OTTDARG00000030787 (1)
  • Ensembl(GRCz11):ENSDARG00000029764 (1)
  • ORTHOLOGY for mef2ca (Chr: 10)
    CITATIONS (81)