ZFIN ID: ZDB-GENE-980526-253
Gene Name: myocyte enhancer factor 2ca
Gene Symbol: mef2ca
Sequence Ontology ID : SO:0000704

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Previous Names: mef2c, hoo, hoover, id:ibd5026, wu:fc05b06, zgc:64184, zgc:85726

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 35 figures from 20 publications
Directly Submitted Expression Data: 6 figures (15 images) from Thisse et al., 2004 [MGC:85726]
  2 figures (3 images) from Kudoh et al., 2001 [ibd5026]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
  adaxial cell, anterior commissure, anterior lateral plate mesoderm, anterior lateral plate mesoderm heart primordium (all 47) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b631 Point Mutation Unknown Missense
  • Zebrafish International Resource Center (ZIRC) (order this)
  • b1086 Point Mutation Exon 2 Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa2569 Point Mutation Unknown Splice Site ENU
    sa31806 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34988 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa34989 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • tn213 Point Mutation Donor Splice Site of Intron 7 Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-mef2ca (1), MO2-mef2ca,mef2d (1), MO3-mef2d,mef2ca (1), MO4-mef2ca (1), MO5-mef2ca (1)
    PHENOTYPE
    Data: 13 figures from 8 publications
    Observed in: basihyal cartilage, bone tissue, branchiostegal ray, branchiostegal ray 3 (all 29) expand
    DISEASE ASSOCIATED WITH mef2ca HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal dominant non-syndromic intellectual disability Chromosome 5q14.3 deletion syndrome 613443
    Mental retardation, stereotypic movements, epilepsy, and/or cerebral malformations 613443
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of transcription from RNA polymerase II promoter (more)
    Cellular Component nucleus (more)
    Molecular Function transcription regulatory region sequence-specific DNA binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002100 (1)
  • InterPro:IPR022102 (1)
  • InterPro:IPR033896 (1)
  • InterPro:IPR036879 (1)
  • PROSITE:PS00350 (1)
  • PROSITE:PS50066 (1)
  • Pfam:PF00319 (1)
  • Pfam:PF12347 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA mef2ca-001 6164
    mef2ca-002 3567
    mef2ca-003 3502
    mef2ca-004 393
    mef2ca-005 393
    mef2ca-006 318
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab2-mef2 (1), Ab2-mef2c (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mef2ca No data available
    MARKER RELATIONSHIPS
    mef2caContained in: [BAC] CH73-215F7 (1) (order this)
    [Fosmid] CH1073-234A2 (1) (order this), CH1073-412J12 (1) (order this), CH1073-418F12 (1) (order this)
    mef2caEncodes: [EST] fc05b06, ibd5026 (order this)
    [cDNA] MGC:64184 (1) (order this), MGC:85726 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131312 (1) 4315bp
    Genomic GenBank:CU462873 (1) 95788bp
    Select Tool
    Polypeptide UniProtKB:Q6NSN7 (1) 491aa
    Sequence Clusters UniGene:3182 (1)
    Sequence Information (all 62)
    OTHER mef2ca GENE PAGES
  • Alliance (1)
  • Gene:30575 (1)
  • VEGA:OTTDARG00000030787 (1)
  • Ensembl(GRCz10):ENSDARG00000029764 (1)
  • ORTHOLOGY for mef2ca (Chr: 10)
    CITATIONS (71)