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ZIRC
ZFIN ID: ZDB-GENE-980526-368
Gene Name: apolipoprotein Eb
Gene Symbol: apoeb
Sequence Ontology ID : SO:0000704

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Previous Names: ApoE-2 (1), apoe, cb82 (1), hm:zeh1311, wu:fa03d06 (1), wu:fa97a11 (1), wu:fc95h12 (1), wu:fj54e06 (1), zeh1311

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have several functions, including anion binding activity; cholesterol binding activity; and cholesterol transfer activity. Predicted to be involved in several processes, including lipid  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa36120 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • scu3 Indel Unknown Unknown TALEN
    Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH apoeb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    age related macular degeneration 1 {?Macular degeneration, age-related} 603075
    Alzheimer's disease 2 Alzheimer disease-2 104310
    hyperlipoproteinemia type III Hyperlipoproteinemia, type III 617347
    {Coronary artery disease, severe, susceptibility to} 617347
    sea-blue histiocytosis Sea-blue histiocyte disease 269600
    Lipoprotein glomerulopathy 611771
    DISEASE ASSOCIATED WITH apoeb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cholesterol efflux (more)
    Cellular Component extracellular matrix (more)
    Molecular Function heparan sulfate proteoglycan binding (more)
    GO Terms (all 44)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000074 (1)
  • Pfam:PF01442 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA apoeb-003 (1) 882
    apoeb-004 (1) 897
    mRNA apoeb-201 (1) 1521
    apoeb-204 (1) 846
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM apoeb
    MARKER RELATIONSHIPS
    apoebContained in: [BAC] DKEY-7F3 (1) (order this)
    apoebEncodes: [EST] cb82 (1) (order this), eu173 (1), fa03d06 (1), fa97a11 (1), fc95h12 (1), fj54e06 (1), zeh1311
    [cDNA] MGC:56515 (1) (order this), MGC:77232 (1) (order this), MGC:171895 (1) (order this)
    apoebHas Artifact: [EST] fa96d02
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131098 (1) 1345bp
    Genomic GenBank:BX004983 (1) 234489bp Blast at MegaBLAST
    Polypeptide UniProtKB:A8KBA6 (1) 281aa
    Sequence Clusters UniGene:23502 (1)
    Sequence Information (all 36)
    ORTHOLOGY for apoeb (Chr: 16)
    CITATIONS (111)