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ZIRC
ZFIN ID: ZDB-GENE-070103-1
Gene Name: von Willebrand factor
Gene Symbol: vwf    Nomenclature History

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Previous Name: si:ch1073-474e24.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Involved in hemostasis. Predicted to localize to the extracellular region. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; atrial fibrillation; end stage renal failure; essential thrombocythemia; and inherited blood coagulation disease (multiple). Is expressed in ball; head; intestinal epithelium; post-vent vasculature; and thrombocyte. Orthologous to human VWF (von Willebrand factor).
Genome Resources: Alliance (1),  Gene:570643 (1),  Ensembl(GRCz11):ENSDARG00000077231 (2)
PHENOTYPE
Data: 2 figures from Carrillo et al., 2010
Observed in:
DISEASE ASSOCIATED WITH vwf HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
von Willebrand's disease 1 Alliance von Willebrand disease, type 1 193400
von Willebrand's disease 2 Alliance von Willebrand disease, types 2A, 2B, 2M, and 2N 613554
von Willebrand's disease 3 Alliance von Willibrand disease, type 3 277480
DISEASE ASSOCIATED WITH vwf VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process hemostasis (more)
Cellular Component extracellular region (more)
GO Terms (all 2)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA vwf-202 (1)    Ensembl 6177
vwf-204 (1)    Ensembl 1332
ncRNA vwf-003 (1) 823
vwf-004 (1) 823
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-vwf polyclonal IHC Sigma-Aldrich
1
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM vwf No data available
MARKER RELATIONSHIPS
vwf Contained in: [Fosmid] CH1073-177N22 (1) (order this), CH1073-464I19 (1) (order this), CH1073-474E24 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001281989 (1) 8713 bp
Genomic GenBank:CU651633 (1) 39383 bp
Select Tool
Polypeptide UniProtKB:E7F9Z1 (1) 2812 aa
Sequence Information (all 18)
ORTHOLOGY for vwf ( Chr: 18 )
CITATIONS (23)