ZFIN ID: ZDB-GENE-050208-382
Gene Name: crumbs cell polarity complex component 1
Gene Symbol: crb1
Sequence Ontology ID : SO:0000704

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Previous Name: si:dkey-114d20.6

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(Including Attributions)
Location: Chr: 22 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011281Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la022267Tg Transgenic Insertion Unknown Unknown DNA
    sa159 Point Mutation Unknown Splice Site ENU
    sa1482 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12558 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14330 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24173 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24174 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa29788 Point Mutation Unknown Splice Site ENU
    Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH crb1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Leber congenital amaurosis 8 Leber congenital amaurosis 8 613835
    retinitis pigmentosa 12 Retinitis pigmentosa-12 600105
    Pigmented paravenous chorioretinal atrophy 172870
    DISEASE ASSOCIATED WITH crb1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process establishment or maintenance of epithelial cell apical/basal polarity (more)
    Cellular Component protein-containing complex (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000152 (1)
  • InterPro:IPR000742 (1)
  • InterPro:IPR001791 (1)
  • InterPro:IPR001881 (1)
  • InterPro:IPR009030 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR013320 (1)
  • InterPro:IPR018097 (1)
  • PROSITE:PS00010 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01187 (1)
  • PROSITE:PS50025 (1)
  • PROSITE:PS50026 (1)
  • Pfam:PF00008 (1)
  • Pfam:PF02210 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA crb1-001 (1) 4427
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM crb1 No data available
    MARKER RELATIONSHIPS
    crb1Contained in: [BAC] CH73-189A7 (1) (order this), CH211-195I21 (1) (order this), DKEY-114D20 (1) (order this)
    crb1Encodes: [cDNA] MGC:195113 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001044943 (1) 4427bp
    Genomic GenBank:CR388178 (1) 171742bp
    Select Tool
    Polypeptide UniProtKB:B3DJP2 (1) 1428aa
    Sequence Clusters UniGene:17713 (1)
    Sequence Information (all 24)
    OTHER crb1 GENE PAGES
  • Alliance (1)
  • Gene:560942 (1)
  • VEGA:OTTDARG00000023452 (1)
  • ORTHOLOGY for crb1 (Chr: 22)
    CITATIONS (28)