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ZIRC
ZFIN ID: ZDB-GENE-030616-135
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Gene Name: calcium channel, voltage-dependent, L type, alpha 1D subunit, a
Gene Symbol: cacna1da
Sequence Ontology ID : SO:0001217

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Previous Names: cacna1d (1), cav1.3a (1), gem, gemini, si:dz136d19.3, si:dz223c6.1

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(Including Attributions)
Location: Chr: 11 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have high voltage-gated calcium channel activity. Involved in detection of mechanical stimulus involved in sensory perception of sound; neuromuscular process controlling balance; and  ...
GENE EXPRESSION
All Expression Data: 9 figures from 5 publications
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la017886Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa1422 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa17298 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • tc323d Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
    • tn004 Point Mutation Unknown Missense ENU
    Targeting reagents:
    PHENOTYPE
    Data: 5 figures from 4 publications
    Observed in:
    DISEASE ASSOCIATED WITH cacna1da HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Primary aldosteronism, seizures, and neurologic abnormalities 615474
    Sinoatrial node dysfunction and deafness 614896
    DISEASE ASSOCIATED WITH cacna1da VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process synapse organization (more)
    Cellular Component basal plasma membrane (more)
    Molecular Function voltage-gated calcium channel activity (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002077 (1)
  • InterPro:IPR005446 (1)
  • InterPro:IPR005821 (1)
  • InterPro:IPR014873 (1)
  • InterPro:IPR027359 (1)
  • InterPro:IPR031649 (1)
  • InterPro:IPR031688 (1)
  • Pfam:PF00520 (1)
  • Pfam:PF08763 (1)
  • Pfam:PF16885 (1)
  • Pfam:PF16905 (1)
    • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cacna1da-003 (1) 546
    Select Tool
    ncRNA cacna1da-004 (1) 840
    Select Tool
    mRNA cacna1da-202 (1) 5981
    Select Tool
    cacna1fb-207 (1) 6662
    Select Tool
    ottdart00000001787 (1) 2432
    Select Tool
    ottdart00000001972 (1) 4125
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cacna1da No data available
    MARKER RELATIONSHIPS
    cacna1da Contained in: [BAC] CH211-243C14 (1) (order this), DKEY-93P1 (1) (order this)
    [PAC] BUSM1-136D19 (1) (order this), BUSM1-223C6 (order this)
    cacna1da Encodes: [cDNA] MGC:194606 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_203484 (1) 6526 bp
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    Genomic GenBank:BX571969 (1) 160905 bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IQX8 (1) 2082 aa
    Select Tool
    Sequence Clusters UniGene:91445 (1)
    Sequence Information (all 45)
    OTHER cacna1da GENE PAGES
  • Alliance (1)
  • Gene:403310 (1)
  • VEGA:OTTDARG00000001673 (1)
  • VEGA:OTTDARG00000001845 (1)
  • VEGA:OTTDARG00000020450 (1)
  • Ensembl(GRCz11):ENSDARG00000102773 (1)
    • ORTHOLOGY for cacna1da ( Chr: 11 )
    CITATIONS (50)