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ZIRC
ZFIN ID: ZDB-GENE-030411-6
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Gene Name: keratin 18a, tandem duplicate 1
Gene Symbol: krt18a.1
Sequence Ontology ID : SO:0001217

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Previous Names: cb83 (1), DreK18 (1), krt18, sb:cb83, wu:fa13f02, wu:fb36b04 (1)

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have structural molecule activity. Predicted to localize to the intermediate filament. Human ortholog(s) of this gene implicated in liver cirrhosis. Is expressed in several structures,  ...
GENE EXPRESSION
All Expression Data: 18 figures from 13 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2001 [cb83]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24263 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa37630 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH krt18a.1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Cirrhosis, cryptogenic 215600
    {Cirrhosis, noncryptogenic, susceptibility to} 215600
    DISEASE ASSOCIATED WITH krt18a.1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component intermediate filament (more)
    Molecular Function structural molecule activity (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002957 (1)
  • InterPro:IPR018039 (1)
  • InterPro:IPR039008 (1)
  • InterPro:IPR042180 (1)
  • PROSITE:PS00226 (1)
  • PROSITE:PS51842 (1)
  • Pfam:PF00038 (1)
    • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA krt18-002 (1) 596
    Select Tool
    krt18-003 (1) 757
    Select Tool
    mRNA krt18-201 (1) 1749
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM krt18a.1
    MARKER RELATIONSHIPS
    krt18a.1 Contained in: [BAC] CH211-133J6 (1) (order this)
    krt18a.1 Contains: [STS] chunp6656, chunp30032
    krt18a.1 Encodes: [EST] cb83 (1) (order this), fa13f02, fb36b04 (1)
    [cDNA] MGC:56024 (1) (order this), MGC:77698 (1) (order this), MGC:191905 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_178437 (1) 1754 bp
    Select Tool
    Genomic GenBank:CR450756 (1) 131145 bp
    Select Tool
    Polypeptide UniProtKB:B2GQG8 (1) 431 aa
    Select Tool
    Sequence Clusters UniGene:39128 (1)
    Sequence Information (all 30)
    OTHER krt18a.1 GENE PAGES
  • Alliance (1)
  • Gene:352912 (1)
  • VEGA:OTTDARG00000021240 (1)
  • Ensembl(GRCz11):ENSDARG00000018404 (1)
    • ORTHOLOGY for krt18a.1 ( Chr: 23 )
    CITATIONS (73)