Gene
krt18a.1
- ID
- ZDB-GENE-030411-6
- Name
- keratin 18a, tandem duplicate 1
- Symbol
- krt18a.1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have structural molecule activity. Predicted to localize to intermediate filament. Human ortholog(s) of this gene implicated in liver cirrhosis. Is expressed in several structures, including EVL; cardiovascular system; gall bladder; head; and pronephric duct. Orthologous to human KRT18 (keratin 18).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 21 figures from 15 publications
- Cross-Species Comparison
- High Throughput Data
-
- GEO (1) Expression Atlas (1) UCSC scRNA-seq (1)
- Thisse Expression Data
-
- cb83 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018039 | Intermediate filament protein, conserved site |
| Domain | IPR039008 | Intermediate filament, rod domain |
| Family | IPR002957 | Keratin, type I |
| Family | IPR027695 | Keratin, type I cytoskeletal 18 |
| Homologous_superfamily | IPR042180 | Intermediate filament, rod domain, coil 1B |
Domain Details Per Protein
| Protein | Length | Intermediate filament protein, conserved site | Intermediate filament, rod domain | Intermediate filament, rod domain, coil 1B | Keratin, type I | Keratin, type I cytoskeletal 18 |
|---|---|---|---|---|---|---|
|
UniProtKB:B2GQG8
|
431 | |||||
|
UniProtKB:Q7ZTS4
|
431 |
Interactions and Pathways
No data available
Plasmids
No data available