ZFIN ID: ZDB-GENE-030131-9
Gene Name: secreted protein, acidic, cysteine-rich (osteonectin)
Gene Symbol: sparc
Sequence Ontology ID : SO:0000704

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Previous Names: hm:zeh0062, osn (1), osteonectin (1)

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Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 23 figures from 11 publications
Directly Submitted Expression Data: 6 figures (16 images) from Thisse et al., 2004 [IMAGE:6910025]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  apical ectodermal ridge pectoral fin bud, blood island, branchiostegal ray 3, ceratohyal cartilage (all 45) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la018906Tg Transgenic Insertion Unknown Unknown DNA
la027518Tg Transgenic Insertion Unknown Unknown DNA
sa22480 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa22481 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-sparc (1), MO2-sparc (1), MO3-sparc (1), MO4-sparc (1)
    PHENOTYPE
    Data: 11 figures from 4 publications
    Observed in: anatomical structure, anterior macula, anterior semicircular canal, blood cell (all 35) expand
    DISEASE ASSOCIATED WITH sparc HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    osteogenesis imperfecta type 17 Osteogenesis imperfecta, type XVII 616507
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process erythrocyte differentiation (more)
    Cellular Component extracellular space (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001999 (1)
  • InterPro:IPR002350 (1)
  • InterPro:IPR003645 (1)
  • InterPro:IPR011992 (1)
  • InterPro:IPR015369 (1)
  • InterPro:IPR018247 (1)
  • InterPro:IPR019577 (1)
  • InterPro:IPR036058 (1)
  • PROSITE:PS00018 (1)
  • PROSITE:PS00612 (1)
  • PROSITE:PS00613 (1)
  • PROSITE:PS51465 (1)
  • Pfam:PF00050 (1)
  • Pfam:PF09289 (1)
  • Pfam:PF10591 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA sparc-001 (1) 1724
    sparc-002 (1) 865
    sparc-003 (1) 520
    sparc-004 (1) 544
    ncRNA sparc-005 (1) 836
    sparc-006 (1) 726
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab1-sparc (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM sparc No data available
    MARKER RELATIONSHIPS
    sparcContained in: [BAC] DKEY-97O1 (1) (order this)
    sparcContains: [SNP] rs3727771, rs3727772, rs3727773, rs3727774
    sparcEncodes: [EST] IMAGE:6910025 (1) (order this), zeh0062
    [cDNA] MGC:86767 (1) (order this)
    sparcHas Artifact: [EST] fa96a08 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001001942 (1) 1688bp
    Genomic GenBank:BX640507 (1) 189019bp
    Select Tool
    Polypeptide UniProtKB:A0A0B5JPZ8 (1) 291aa
    Sequence Clusters UniGene:75554 (1)
    Sequence Information (all 22)
    OTHER sparc GENE PAGES
  • Alliance (1)
  • Gene:321357 (1)
  • VEGA:OTTDARG00000020966 (1)
  • Ensembl(GRCz10):ENSDARG00000019353 (1)
  • ORTHOLOGY for sparc (Chr: 14)
    CITATIONS (55)