ZFIN ID: ZDB-GENE-030114-5
Gene Name: IMP (inosine 5'-monophosphate) dehydrogenase 2
Gene Symbol: impdh2    Nomenclature History

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Previous Names: cb635 (1), wu:fb64g02, wu:fc43f09

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have IMP dehydrogenase activity; metal ion binding activity; and nucleotide binding activity. Involved in circadian rhythm. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including digestive system; immature eye; mesoderm; muscle; and nervous system. Orthologous to human IMPDH2 (inosine monophosphate dehydrogenase 2).
Genome Resources: Alliance (1),  Gene:317745 (1),  Ensembl(GRCz11):ENSDARG00000006900 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa41221 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-impdh2 N/A 1
    DISEASE ASSOCIATED WITH impdh2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    [IMPDH2 enzyme activity, variation in] 617995
    DISEASE ASSOCIATED WITH impdh2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process circadian rhythm (more)
    Cellular Component cytoplasm (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA impdh2-201 (1)    Ensembl 2335
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM impdh2 No data available
    MARKER RELATIONSHIPS
    impdh2 Contained in: [BAC] DKEY-90L2 (1) (order this)
    impdh2 Encodes: [EST] cb635 (1) (order this), fb64g02 (1), fc43f09, IMAGE:7166281 (1)
    [cDNA] MGC:55942 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201464 (1) 2226 nt
    Genomic GenBank:CR382331 (1) 80921 nt
    Select Tool
    Polypeptide UniProtKB:B0UXP9 (1) 514 aa
    Sequence Information (all 22)
    ORTHOLOGY for impdh2 ( Chr: 8 )
    CITATIONS (30)