Gene

impdh2

ID
ZDB-GENE-030114-5
Name
IMP (inosine 5'-monophosphate) dehydrogenase 2
Symbol
impdh2 Nomenclature History
Previous Names
  • cb635 (1)
  • wu:fb64g02
  • wu:fc43f09
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have IMP dehydrogenase activity; metal ion binding activity; and nucleotide binding activity. Involved in circadian rhythm. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including digestive system; immature eye; mesoderm; muscle; and nervous system. Orthologous to human IMPDH2 (inosine monophosphate dehydrogenase 2).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Li et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With impdh2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
[IMPDH2 enzyme activity, variation in] 617995
Associated With impdh2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR015875 IMP dehydrogenase / GMP reductase, conserved site
Domain IPR000644 CBS domain
Domain IPR001093 IMP dehydrogenase/GMP reductase
Family IPR005990 Inosine-5'-monophosphate dehydrogenase
Homologous_superfamily IPR013785 Aldolase-type TIM barrel
Domain Details Per Protein
Protein Length Aldolase-type TIM barrel CBS domain IMP dehydrogenase/GMP reductase IMP dehydrogenase / GMP reductase, conserved site Inosine-5'-monophosphate dehydrogenase
UniProtKB:B0UXP9 514
UniProtKB:Q7ZYW9 514
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations