ZFIN ID: ZDB-GENE-010111-1
Gene Name: SRY-box transcription factor 19b
Gene Symbol: sox19b    Nomenclature History

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Previous Names: sox31 (1), cb174 (1), fb76c08, fe16f11, fe24f11, id:ibd3529 (1), sb:cb174 (1), wu:fb76c08 (1), wu:fe16f11 (1), wu:fe24f11 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Contributes to DNA-binding transcription factor activity. Involved in dorsal/ventral axis specification; epiboly involved in gastrulation with mouth forming second; and positive regulation of DNA-binding transcription factor activity. Predicted to localize to nucleus and transcription regulator complex. Is expressed in several structures, including central nervous system; epiblast; neural keel; neural tube; and presumptive structure. Orthologous to human SOX15 (SRY-box transcription factor 15).
Genome Resources: Alliance (1),  Gene:64812 (1),  Ensembl(GRCz11):ENSDARG00000040266 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-sox19b N/A 4
MO2-sox19b N/A 4
MO3-sox19b N/A 1
MO4-sox19b N/A 1
MO5-sox19b N/A 2
MO6-sox19b N/A 3
MO7-sox19b N/A 1
DISEASE ASSOCIATED WITH sox19b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH sox19b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process dorsal/ventral pattern formation (more)
Cellular Component transcription regulator complex (more)
Molecular Function CONTRIBUTES_TO   DNA-binding transcription factor activity (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA sox19b-201 (1)    Ensembl 2561
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab4-sox2 polyclonal IgG Goat WB R&D Systems
5
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM sox19b No data available
MARKER RELATIONSHIPS
sox19b Contained in: [BAC] DKEY-3K24 (1) (order this)
sox19b Encodes: [EST] cb174 (1) (order this), fb76c08, fe16f11, fe24f11, ibd3529 (1)
[cDNA] MGC:63822 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131702 (1) 2556 nt
Genomic GenBank:CR848737 (1) 158396 nt
Select Tool
Polypeptide UniProtKB:F1R211 (1) 293 aa
Sequence Information (all 22)
ORTHOLOGY for sox19b ( Chr: 7 )
CITATIONS (59)