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ZIRC
ZFIN ID: ZDB-GENE-980526-333
Gene Name: SRY-box transcription factor 3
Gene Symbol: sox3
Sequence Ontology ID : SO:0001217

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Previous Names: id:ibd2036 (1), sb:cb493 (1), wu:fd02a08 (1), zgc:110279 (1)

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(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Contributes to DNA-binding transcription factor activity. Involved in several processes, including nervous system development; otic placode development; and otic placode formation. Predicted to  ...
GENE EXPRESSION
All Expression Data: 92 figures from 48 publications
Directly Submitted Expression Data: 4 figures (4 images) from Kudoh et al., 2001 [ibd2036]
  6 figures (32 images) from Thisse et al., 2001 [cb493]
  12 figures (43 images) from Rauch et al., 2003 [fc66h05]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Juvenile:Days 30-44 (30d-45d, 10 mm, adult fins/pigment)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh276 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • fh277 Point Mutation Unknown Unknown ENU
    sox3_unrecovered Point Mutation Unknown Unknown ENU
    x52 Small Deletion Unknown Frameshift, Premature Stop CRISPR
    x53 Indel Unknown Frameshift, Premature Stop CRISPR
    Targeting reagents:
    DISEASE ASSOCIATED WITH sox3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Mental retardation, X-linked, with isolated growth hormone deficiency 300123
    Panhypopituitarism, X-linked 312000
    DISEASE ASSOCIATED WITH sox3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of DNA-binding transcription factor activity (more)
    Cellular Component nucleus (more)
    Molecular Function CONTRIBUTES_TO   DNA-binding transcription factor activity (more)
    GO Terms (all 14)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA sox3-201 (1) 1764
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    MARKER RELATIONSHIPS
    sox3 Contained in: [BAC] CH211-143L19 (1) (order this), CH211-285J6 (1) (order this)
    sox3 Encodes: [EST] cb493 (1) (order this), fc66h05 (1) (order this), fd02a08 (1), ibd2036 (1) (order this)
    [cDNA] MGC:110279 (1) (order this), MGC:174245 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001001811 (1) 1781 bp
    Genomic GenBank:BX088596 142350 bp
    Select Tool
    Polypeptide UniProtKB:A9JSZ3 (1) 300 aa
    Sequence Clusters UniGene:104569 (1)
    Sequence Information (all 30)
    ORTHOLOGY for sox3 ( Chr: 14 )
    CITATIONS (120)