FIGURE

Fig. 1

ID

ZDB-FIG-240528-20

Publication

Tuttle et al., 2024 - Single-cell analysis of Rohon-Beard neurons implicates Fgf signaling in axon maintenance and cell survival

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Fig. 1

Identification of transcriptionally distinct RB subpopulations. A, Unsupervised clustering and UMAP reduction diagram of cells derived from trunks of day 4 (Kelly et al., 2023) and day 7 larvae. B,C, Feature plots identifying neurons (B) and glia (C). D,E, Feature plots of two RB markers, isl2a and prdm14, identifying clusters 24 and 29 as RBs. F,G, Unsupervised subclustering and UMAP reduction diagram of RB cells. H, Bar plot showing cell numbers for each cluster. I, Heat map showing top five DE genes for each cluster. J, Dot plot profile of genes expressed in all RBs (isl2a, fgf13a, and prdm14), kitb+ cluster (kitb and trpc4a), calca+ cluster (calca and tmem178), and adcyap1a+ cluster (adcyap1a and prickle1a). K–M, Volcano plots showing top DE genes in each RB cluster.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Neurosci.