FIGURE

Fig. S6

ID

ZDB-FIG-200805-26

Publication

Ye et al., 2020 - p53 isoform Δ113p53 promotes zebrafish heart regeneration by maintaining redox homeostasis

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Fig. S6

Depletion of Δ113p53 has little effects on DNA damage response and apoptotic activity during heart regeneration. (A-B) Cryosections of Tg(myl7:nDsRed); Δ113p53^+/+ (A) and Tg(myl7:nDsRed); Δ113p53^M/M(B) hearts at 14 dpa were co-stained by anti-DsRed (in red) and anti-γ-H2AX (in green) antibodies. Framed areas were magnified in A’ and B’. (C-D) TUNEL assay (in green) and co-immunostaining with anti-DsRed antibody (in red) were performed on cryosections of Tg(myl7:nDsRed);Δ113p53^+/+ (C) and Tg(myl7:nDsRed); Δ113p53^M/M (D) hearts at 14 dpa. Framed areas were magnified in C’ and D’. The representative picture was taken from 6 hearts in each group. Scale bar, 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell Death Dis.