FIGURE

Figure 5

ID

ZDB-FIG-200406-53

Publication

Guo et al., 2020 - A Rare KIF1A Missense Mutation Enhances Synaptic Function and Increases Seizure Activity

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Figure 5

Effect of mutant KIF1A on neuronal development. (A) Representative image of cultured primary hippocampal neurons obtained through a Sholl analysis. The radius interval between circles was 10 μm per step and ranged from 10 to 210 μm from the center of the neuronal soma. (B) Sholl analysis of neurons expressing the mutant (n = 15 neurons) or wild-type protein (n = 13 neurons) (two-way ANOVA). (C, D) Number of primary and secondary neurites of neurons expressing the mutant (n = 15 neurons) or wild-type protein (n = 13 neurons) (Student's t test).

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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