|ZFIN ID: ZDB-FIG-191010-4|
Collagen type II is present in the semicircular canal tissues of cog4−/− mutants. Co-labeling of Collagen type II (red) and phalloidin (green) in cog4 sibling (A; n = 22 larvae) and cog4−/− mutant larvae (B, C; n = 23 larvae). White stars indicate the pillars (A–C). White arrowheads point to the otic capsule (A–C). Blue arrowheads points to a delayed ventral projection (C). Anterior to the left and dorsal to the top. 5 dpf.
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Reprinted from Mechanisms of Development, 155, Clément, A., Blanco-Sánchez, B., Peirce, J.L., Westerfield, M., Cog4 is required for protrusion and extension of the epithelium in the developing semicircular canals, 1-7, Copyright (2018) with permission from Elsevier. Full text @ Mech. Dev.