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ZFIN ID: ZDB-FIG-180816-2
Davis et al., 2018 - ETS transcription factor Etsrp / Etv2 is required for lymphangiogenesis and directly regulates vegfr3 / flt4 expression. Developmental Biology   440(1):40-52 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage: Day 4
PHENOTYPE:
Fish:
Observed In:
Stage: Day 4

Fig. 2

Thoracic duct is absent in etv2 mutant larvae. Confocal microscopy analysis of the thoracic duct (arrows) in wild-type siblings and etv2 mutant larvae in fli1a:GFP; prox1a:RFP background at 4 dpf. Note the absence of the thoracic duct (asterisks) and abnormal vascular patterning in etv2 mutants. (A′,B′) Higher magnification images of larvae in A,B. DA, dorsal aorta, PCV, posterior cardinal vein.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
EGFP nim5Tg ; y1Tg ; etv2y11/y11 standard conditions Day 4 dorsal aorta IFL
Day 4 trunk vasculature IFL
y1Tg ; nim5Tg standard conditions Day 4 dorsal aorta IFL
Day 4 trunk vasculature IFL
TagRFP nim5Tg ; y1Tg ; etv2y11/y11 standard conditions Day 4 lymph vasculature IFL
Day 4 Not Detected thoracic duct IFL
y1Tg ; nim5Tg standard conditions Day 4 lymph vasculature IFL
Day 4 thoracic duct IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
nim5Tg ; y1Tg ; etv2y11/y11 standard conditions Day 4 thoracic duct absent, abnormal
Day 4 thoracic duct TagRFP expression absent, abnormal
Day 4 trunk vasculature morphology, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Biology, 440(1), Davis, J.A., Koenig, A.L., Lubert, A., Chestnut, B., Liu, F., Desai, S.P., Winkler, T., Pociute, K., Choi, K., Sumanas, S., ETS transcription factor Etsrp / Etv2 is required for lymphangiogenesis and directly regulates vegfr3 / flt4 expression, 40-52, Copyright (2018) with permission from Elsevier. Full text @ Dev. Biol.