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ZIRC
ZFIN ID: ZDB-FIG-180518-2
Eachus et al., 2017 - Genetic disruption of 21-hydroxylase in zebrafish causes interrenal hyperplasia. Endocrinology   158(12):4165-4173 Full text @ Endocrinology
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Anatomical Term:
Stage: Day 5
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage: Day 5

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
fkbp5 WT standard conditions Day 5 whole organism RTPCR
WT hypertonic, chemical treatment: sodium chloride Day 5 whole organism RTPCR
cyp21a2uob2122/uob2122 standard conditions Day 5 whole organism RTPCR
cyp21a2uob2122/uob2122 hypertonic, chemical treatment: sodium chloride Day 5 whole organism RTPCR
pck1 WT standard conditions Day 5 whole organism RTPCR
WT hypertonic, chemical treatment: sodium chloride Day 5 whole organism RTPCR
cyp21a2uob2122/uob2122 standard conditions Day 5 whole organism RTPCR
cyp21a2uob2122/uob2122 hypertonic, chemical treatment: sodium chloride Day 5 whole organism RTPCR
pomca WT standard conditions Day 5 whole organism RTPCR
WT hypertonic, chemical treatment: sodium chloride Day 5 whole organism RTPCR
cyp21a2uob2122/uob2122 standard conditions Day 5 whole organism RTPCR
cyp21a2uob2122/uob2122 hypertonic, chemical treatment: sodium chloride Day 5 whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT hypertonic, chemical treatment: sodium chloride Day 5 whole organism fkbp5 expression increased amount, abnormal
Day 5 whole organism pomca expression increased amount, abnormal
Day 5 whole organism pck1 expression increased amount, abnormal
cyp21a2uob2122/uob2122 standard conditions Day 5 whole organism fkbp5 expression decreased amount, abnormal
Day 5 whole organism pck1 expression decreased amount, abnormal
Day 5 whole organism pomca expression increased amount, abnormal
cyp21a2uob2122/uob2122 hypertonic, chemical treatment: sodium chloride Day 5 cellular response to osmotic stress disrupted, abnormal
Day 5 whole organism fkbp5 expression decreased amount, abnormal
Day 5 whole organism pck1 expression decreased amount, abnormal
Day 5 whole organism pomca expression increased amount, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Endocrinology for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Endocrinology