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General Information
ZIRC
ZFIN ID: ZDB-GENE-030513-2
Gene Name: proopiomelanocortin a
Gene Symbol: pomca
Sequence Ontology ID : SO:0000704

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Previous Names: pomc, ACTH, beta-endorphin, MSH, si:bz36d5.2

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits neuropeptide hormone activity. Involved in several processes, including melanosome localization; multicellular organismal response to stress; and regulation of hematopoietic stem cell  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
DISEASE ASSOCIATED WITH pomca HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
obesity {Obesity, early-onset, susceptibility to} 601665
Obesity, adrenal insufficiency, and red hair due to POMC deficiency 609734
DISEASE ASSOCIATED WITH pomca VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process neuropeptide signaling pathway (more)
Cellular Component extracellular region (more)
Molecular Function neuropeptide hormone activity (more)
GO Terms (all 11)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA pomca-201 (1) 1224
GENE PRODUCT DESCRIPTION No description available
INTERACTIONS AND PATHWAYS
ANTIBODIES
PLASMIDSNo data available
MARKER RELATIONSHIPS
pomcaContained in: [BAC] RP71-36D5 (1) (order this)
pomcaEncodes: [cDNA] MGC:162115 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_181438 (1) 1248bp
Genomic GenBank:AL590149 (1) 167272bp
Select Tool
Polypeptide UniProtKB:Q7ZT18 (1) 222aa
Sequence Clusters UniGene:19934 (1)
Sequence Information (all 18)
ORTHOLOGY for pomca (Chr: 17)
CITATIONS (120)