Gene

fkbp5

ID
ZDB-GENE-030616-630
Name
FKBP prolyl isomerase 5
Symbol
fkbp5 Nomenclature History
Previous Names
  • si:zc263a23.8
  • wu:fc31g11
  • wu:fl87b03
  • zgc:64082
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in chaperone-mediated protein folding and protein peptidyl-prolyl isomerization. Predicted to localize to cytoplasm. Is expressed in gut; head; and regenerating fin. Human ortholog(s) of this gene implicated in major depressive disorder. Orthologous to human FKBP5 (FKBP prolyl isomerase 5).
Genome Resources
Note
None
Expression
All Expression Data
13 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fkbp5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
endogenous depression Alliance {Major depressive disorder and accelerated response to antidepressant drug treatment} 608516
Associated With fkbp5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain
Domain IPR013026 Tetratricopeptide repeat-containing domain
Family IPR031210 Peptidyl-prolyl cis-trans isomerase FKBP5
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
Repeat IPR019734 Tetratricopeptide repeat
Domain Details Per Protein
Protein Length FKBP-type peptidyl-prolyl cis-trans isomerase domain Peptidyl-prolyl cis-trans isomerase FKBP5 Tetratricopeptide-like helical domain superfamily Tetratricopeptide repeat Tetratricopeptide repeat-containing domain
UniProtKB:Q801U5 453
UniProtKB:A0A2R8RWP8 470
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations