FIGURE

Fig. 1 S1

ID
ZDB-FIG-180208-5
Publication
Donat et al., 2018 - Heg1 and Ccm1/2 proteins control endocardial mechanosensitivity during zebrafish valvulogenesis
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Fig. 1 S1

Whole-mount in situ hybridization of heg1 cardiac expression.

(A) At 30 hpf, heg1 is expressed throughout the entire endocardium. (B) Later, at 48 hpf, heg1 expression becomes restricted to high fluid shear stress regions of the endocardium including the atrioventricular canal (AVC). (C) The strong expression of heg1 at the AVC persists at 72 hpf. (D) Expression of heg1 was reduced in morphant embryos lacking blood-flow [troponin T type 2a (tnnt2a)] at 48 hpf. A: atrium, V: ventricle, OFT: outflow tract, arrowheads in B, C, and D point at the AVC.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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