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General Information
ZIRC
ZFIN ID: ZDB-FIG-171130-10
Xiong et al., 2015 - The Kinase Activity-deficient Isoform of the Protein Araf Antagonizes Ras/Mitogen-activated Protein Kinase (Ras/MAPK) Signaling in the Zebrafish Embryo. The Journal of biological chemistry   290(42):25512-21 Full text @ J. Biol. Chem.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Shield to 75%-epiboly
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Shield to 75%-epiboly

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
chrd TU standard conditions Shield whole organism dorsal region ISH
TU + MO1-araf + MO2-araf standard conditions Shield whole organism dorsal region ISH
gata2a TU standard conditions Shield whole organism ventral region ISH
TU + MO1-araf + MO2-araf standard conditions Shield whole organism ventral region ISH
gsc TU standard conditions Shield whole organism dorsal region ISH
TU + MO1-araf + MO2-araf standard conditions Shield whole organism dorsal region ISH
hoxb1b TU standard conditions 75%-epiboly neuroectoderm posterior region ISH
TU + MO1-araf + MO2-araf standard conditions 75%-epiboly neuroectoderm posterior region ISH
otx2b TU standard conditions 75%-epiboly neuroectoderm anterior region ISH
TU + MO1-araf + MO2-araf standard conditions 75%-epiboly neuroectoderm anterior region ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
TU + MO1-araf + MO2-araf standard conditions Shield whole organism dorsal region gsc expression increased distribution, abnormal
Shield whole organism dorsal region chrd expression increased distribution, abnormal
Shield whole organism ventral region gata2a expression decreased distribution, abnormal
75%-epiboly neuroectoderm anterior region otx2b expression increased distribution, abnormal
75%-epiboly neuroectoderm posterior region hoxb1b expression increased distribution, abnormal
Full text @ J. Biol. Chem.