ZFIN ID: ZDB-GENE-980526-260
Gene Name: GATA binding protein 2a
Gene Symbol: gata2a
Sequence Ontology ID : SO:0000704

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Previous Names: gata2 (1), gta2 (1), zg2

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(Including Attributions)
Location: Chr: 11 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding activity transcription factor activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity; involved in several  ...
GENE EXPRESSION
All Expression Data: 161 figures from 112 publications
Directly Submitted Expression Data: 6 figures (20 images) from Thisse et al., 2005 [eu473]
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
um27 Small Deletion Unknown Frameshift, Premature Stop ZINC_FINGER_NUCLEASE
Targeting reagents:
PHENOTYPE
Data: 17 figures from 9 publications
Observed in:
DISEASE ASSOCIATED WITH gata2a HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
acute myeloid leukemia {Leukemia, acute myeloid, susceptibility to} 601626
myelodysplastic syndrome {Myelodysplastic syndrome, susceptibility to} 614286
Immunodeficiency 21 614172
Emberger syndrome 614038
DISEASE ASSOCIATED WITH gata2a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process primitive hemopoiesis (more)
Cellular Component nucleus (more)
Molecular Function DNA-binding transcription factor activity (more)
GO Terms (all 17)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000679 (1)
  • InterPro:IPR013088 (1)
  • InterPro:IPR016374 (1)
  • InterPro:IPR039355 (1)
  • PROSITE:PS00344 (1)
  • PROSITE:PS50114 (1)
  • Pfam:PF00320 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gata2a-202 (1) 2533
    gata2a-203 (1) 781
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gata2a
    MARKER RELATIONSHIPS
    gata2aContained in: [BAC] CH211-63I20 (1) (order this)
    gata2aEncodes: [EST] eu473 (1)
    [cDNA] MGC:63885 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131233 (1) 2571bp
    Genomic GenBank:AL928619 (1) 158847bp
    Select Tool
    Polypeptide UniProtKB:A0A2R9YJP8 (1) 460aa
    Sequence Clusters UniGene:356 (1)
    Sequence Information (all 25)
    OTHER gata2a GENE PAGES
  • Alliance (1)
  • Gene:30480 (1)
  • VEGA:OTTDARG00000020332 (1)
  • Ensembl(GRCz11):ENSDARG00000059327 (2)
  • ORTHOLOGY for gata2a (Chr: 11)
    CITATIONS (302)