Gene
gata2a
- ID
- ZDB-GENE-980526-260
- Name
- GATA binding protein 2a
- Symbol
- gata2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in animal organ development and dorsal aorta morphogenesis. Predicted to localize to nuclear chromatin. Is expressed in several structures, including hematopoietic system; mesoderm; nervous system; neural tube; and trunk vasculature. Human ortholog(s) of this gene implicated in acute myeloid leukemia; immunodeficiency 21; mental depression; myelodysplastic syndrome; and myeloid leukemia. Orthologous to human GATA2 (GATA binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 177 figures from 125 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu473 (20 images)
Wild Type Expression Summary
- All Phenotype Data
- 21 figures from 11 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Transcription factor GATA | Transcription factor, GATA-2/3 | Zinc finger, GATA-type | Zinc finger, NHR/GATA-type |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q709
|
397 | ||||
|
UniProtKB:Q7T3G1
|
456 | ||||
|
UniProtKB:A0A8M3AXB8
|
460 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
gata2a-201
(1)
|
Ensembl | 2829 nt | |
| mRNA |
gata2a-202
(1)
|
Havana | 2533 nt | |
| mRNA |
gata2a-203
(1)
|
Havana | 781 nt |
Interactions and Pathways
No data available
Plasmids