ZFIN ID: ZDB-FIG-170921-1
Lin et al., 2017 - Establishment of a congenital amegakaryocytic thrombocytopenia model and a thrombocyte-specific reporter line in zebrafish. Leukemia   31(5):1206-1216 Full text @ Leukemia
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: Prim-25 to Adult
PHENOTYPE:
Fish:
Observed In:
Stage Range: Protruding-mouth to Adult

Fig. 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP la2Tg standard conditions Day 4 thrombocyte IHC
la2Tg ; mplsm10/sm10 standard conditions Day 4 thrombocyte IHC
gp1bb mplsm10/sm10(AB) standard conditions Day 4 whole organism RTPCR
gp9 mplsm10/sm10(AB) standard conditions Day 4 whole organism RTPCR
itga2b mplsm10/sm10(AB) standard conditions Day 4 whole organism RTPCR
Adult blood RTPCR
Adult head kidney RTPCR
lrrc32 mplsm10/sm10(AB) standard conditions Day 4 whole organism RTPCR
Adult blood RTPCR
Adult head kidney RTPCR
myb AB standard conditions Prim-25 hematopoietic multipotent progenitor cell ISH
Day 4 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
mplsm10/sm10(AB) standard conditions Prim-25 hematopoietic multipotent progenitor cell ISH
Day 4 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Adult head kidney RTPCR
nfe2 mplsm10/sm10(AB) standard conditions Day 4 whole organism RTPCR
runx1 mplsm10/sm10(AB) standard conditions Adult head kidney RTPCR
zfpm1 mplsm10/sm10(AB) standard conditions Day 4 whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
la2Tg ; mplsm10/sm10 standard conditions Protruding-mouth thrombocyte decreased amount, abnormal
Day 4 thrombocyte decreased amount, abnormal
Day 5 thrombocyte decreased amount, abnormal
Days 7-13 thrombocyte decreased amount, abnormal
Adult blood thrombocyte decreased amount, abnormal
Adult head kidney hematopoietic multipotent progenitor cell decreased amount, abnormal
Adult head kidney thrombocyte decreased amount, abnormal
mplsm10/sm10(AB) standard conditions Day 4 whole organism gp9 expression decreased amount, abnormal
mplsm10/sm10(AB) standard conditions Day 4 whole organism gp1bb expression decreased amount, abnormal
mplsm10/sm10(AB) standard conditions Day 4 whole organism itga2b expression decreased amount, abnormal
mplsm10/sm10(AB) standard conditions Day 4 whole organism nfe2 expression decreased amount, abnormal
mplsm10/sm10(AB) standard conditions Day 4 whole organism zfpm1 expression decreased amount, abnormal
mplsm10/sm10(AB) standard conditions Day 4 whole organism lrrc32 expression decreased amount, abnormal
mplsm10/sm10(AB) standard conditions Adult blood lrrc32 expression decreased amount, abnormal
mplsm10/sm10(AB) standard conditions Adult blood itga2b expression decreased amount, abnormal
mplsm10/sm10(AB) standard conditions Adult head kidney runx1 expression decreased amount, abnormal
mplsm10/sm10(AB) standard conditions Adult head kidney myb expression decreased amount, abnormal
mplsm10/sm10(AB) standard conditions Adult head kidney lrrc32 expression decreased amount, abnormal
mplsm10/sm10(AB) standard conditions Adult head kidney itga2b expression decreased amount, abnormal
Full text @ Leukemia