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ZIRC
ZFIN ID: ZDB-GENE-051031-1
Gene Name: integrin, alpha 2b
Gene Symbol: itga2b
Sequence Ontology ID : SO:0001217

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Previous Names: CD41 (1), GPIIb (1), si:dkey-27b3.6 (1)

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in angiogenesis; blood coagulation; and endothelial cell proliferation. Localizes to the integrin complex. Human ortholog(s) of this gene implicated in Glanzmann's thrombasthenia;  ...
GENE EXPRESSION
All Expression Data: 20 figures from 15 publications
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
DISEASE ASSOCIATED WITH itga2b HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Glanzmann's thrombasthenia Glanzmann thrombasthenia 273800
platelet-type bleeding disorder 16 Bleeding disorder, platelet-type, 16, autosomal dominant 187800
Thrombocytopenia, neonatal alloimmune, BAK antigen related
DISEASE ASSOCIATED WITH itga2b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process blood coagulation (more)
Cellular Component integrin complex (more)
Molecular Function protein binding (more)
GO Terms (all 9)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA itga2b-201 (1) 3755
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIES
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM itga2b
MARKER RELATIONSHIPS
itga2b Contained in: [BAC] CH73-54A8 (order this)
itga2b Encodes: [cDNA] MGC:194612 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001003857 (1) 3673 bp
Genomic GenBank:CT573446 (1) 75900 bp
Select Tool
Polypeptide UniProtKB:B3DIZ6 (1) 1037 aa
Sequence Clusters UniGene:85730 (1)
Sequence Information (all 12)
ORTHOLOGY for itga2b ( Chr: 3 )
CITATIONS (66)